VWC2 and ZNF837

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VWC2	ZNF837
Description		von Willebrand factor C domain containing 2	zinc finger protein 837
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Interstitial Matrix Extracellular Space Extracellular Matrix AMPA Glutamate Receptor Complex Synapse Extrinsic Component Of Postsynaptic Membrane Glutamatergic Synapse	Nucleus
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Neuron Differentiation Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Blood protein levels ( 30072576) Body mass index ( 25673413 28892062) Lung cancer in never smokers ( 28604730) Neurological blood protein biomarker levels ( 31320639) Post bronchodilator FEV1/FVC ratio ( 26634245) Pursuit maintenance gain ( 29064472) Serum thyroid-stimulating hormone levels ( 25436638) tricyclic pyrone compound response (IC50) ( 33610756)
Interacting Genes		57 interacting genes: ABHD15 ADAMTSL4 ATPAF2 CAMLG CATSPER1 CNNM3 CRY2 CYSRT1 ENKD1 FAM90A1 FBXW5 FUCA2 GET3 GNE HAPLN2 HOXA1 HPCA HPCAL1 KANK2 KPRP KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 LCE1A LCE1C LCE1F LCE2C LCE2D LCE3A LCE3D LCE3E LCE4A LCE5A NTM OTX1 PFKFB1 POU4F2 PRPF31 SCNM1 SGTB SHFL SPRY1 TRAPPC14 UBQLN1 UBQLN2 VASN YY1 ZNF319 ZNF417 ZNF490 ZNF497 ZNF587 ZNF774 ZNF837	77 interacting genes: BAHD1 CARD10 CATSPER1 CCDC125 CCDC136 CCNDBP1 CDC37 CHIC2 CLK2 CYSRT1 DHX57 DVL3 EFEMP2 EHMT2 FSD2 GOLGA6L9 GPATCH2L HOXA1 KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-12 KRTAP4-5 KRTAP5-9 MDFI MTUS2 MYO15B NBPF19 NOTCH2NLA PCSK5 PHF19 PPARD PPP1R37 PRPF31 RBMY1F RBMY1J RSPO2 SPRED2 SPRY1 TCEANC TNS2 TRIM41 TRMT2A UBE2I VWC2 ZBTB24 ZBTB48 ZBTB8A ZNF121 ZNF124 ZNF165 ZNF17 ZNF202 ZNF250 ZNF275 ZNF330 ZNF408 ZNF417 ZNF473 ZNF497 ZNF524 ZNF526 ZNF552 ZNF587 ZNF639 ZNF648 ZNF655 ZNF764 ZNF792 ZNF835 ZRANB1 ZSCAN21
Entrez ID		375567	116412
HPRD ID		18271
Ensembl ID		ENSG00000188730	ENSG00000152475
Uniprot IDs		Q2TAL6	Q96EG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Epidermis Development Keratinization Tissue Development Protein Binding Intermediate Filament GET Complex Identical Protein Binding Keratin Filament	Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Keratin Filament Intermediate Filament Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Hair Cycle Nucleus Negative Regulation Of Lens Fiber Cell Differentiation Regulation Of Macromolecule Metabolic Process Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding
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