KCNC1 and KCNH1

Number of citations of the paper that reports this interaction (PMID 12060745)
33

Data Source:
BioGRID (two hybrid)

		KCNC1	KCNH1
Gene Name		potassium channel, voltage gated Shaw related subfamily C, member 1	potassium channel, voltage gated eag related subfamily H, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axolemma Dendrite Membrane Neuronal Cell Body Membrane	Nuclear Inner Membrane Nucleoplasm Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Kinesin Binding	Phosphorelay Sensor Kinase Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Phosphorelay Signal Transduction System Potassium Ion Transport Synaptic Transmission Myoblast Fusion Signal Transduction By Phosphorylation Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Potassium Ion Transmembrane Transport
Pathways		Potassium Channels Voltage gated Potassium channels	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS			Circulating vasoactive peptide levels ( 23381795)
Protein-Protein Interactions		4 interactors: ANK3 KCNG3 KCNH1 KCNV2	9 interactors: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 SDCBP WDYHV1
Entrez ID		3746	3756
HPRD ID		15936	04492
Ensembl ID		ENSG00000129159
Uniprot IDs		K4DI87 P48547 Q3KNS8	O95259
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transmembrane Transport Regulation Of Ion Transport Potassium Ion Transmembrane Transport Potassium Ion Transport Synaptic Transmission Monovalent Inorganic Cation Transport Maintenance Of Protein Location In Plasma Membrane Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Metal Ion Transport Cell-cell Signaling Cation Transmembrane Transport Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Cell Communication By Electrical Coupling Cation Transport Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Cellular Response To Magnesium Ion Ion Transmembrane Transport Protein Homooligomerization Regulation Of Membrane Potential Regulation Of Membrane Depolarization During Action Potential Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Action Potential Transmembrane Transport Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Peptidyl-histidine Phosphorylation Regulation Of Cell Communication By Electrical Coupling Cytoskeletal Anchoring At Plasma Membrane Protein Oligomerization Cellular Component Assembly Transport Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport Phosphorelay Signal Transduction System Positive Regulation Of Sodium Ion Transmembrane Transport Magnesium Ion Homeostasis Response To Magnesium Ion Signaling Negative Regulation Of Cation Channel Activity Cell Communication Myoblast Fusion Negative Regulation Of Potassium Ion Transport Membrane Assembly Golgi To Plasma Membrane Protein Transport Membrane Biogenesis Neuronal Action Potential Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Protein Targeting To Membrane	Synaptic Transmission Regulation Of Ion Transmembrane Transport Cell-cell Signaling Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Ion Transport Monovalent Inorganic Cation Transport Protein Homooligomerization Energy Derivation By Oxidation Of Organic Compounds Metal Ion Transport Cation Transmembrane Transport Generation Of Precursor Metabolites And Energy Protein Oligomerization Cation Transport Ion Transmembrane Transport Energy Reserve Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Transmembrane Transport Ion Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Component Assembly Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Peptidyl-histidine Phosphorylation Transport Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Detection Of Calcium Ion Substrate-dependent Cell Migration, Cell Extension Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Protein Complex Assembly Regulation Of Cellular Localization Phosphorelay Signal Transduction System Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Signaling Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Cell Communication Polysaccharide Catabolic Process
Tagcloud ?			1c currents eag eag1 elk erg erg1 governed heag1 herg imbalance immuno itim kcnh2 kv10 kv11 kv12 nothing phosphatases pp1 prototypes ptp ptpn6 qt shp src40 subfamilies superfamily underlie
Tagcloud (Difference) ?			1c currents eag eag1 elk erg erg1 governed heag1 herg imbalance immuno itim kcnh2 kv10 kv11 kv12 nothing phosphatases pp1 prototypes ptp ptpn6 qt shp src40 subfamilies superfamily underlie
Tagcloud (Intersection) ?