ABCC6 and A1BG

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ABCC6	A1BG
Gene Name		ATP-binding cassette, sub-family C (CFTR/MRP), member 6	alpha-1-B glycoprotein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane	Extracellular Region Extracellular Space Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Transporter Activity ATP Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances	Molecular_function
	Biological Process	Transport Visual Perception Response To Drug Transmembrane Transport	Biological_process
Pathways		ABC-family proteins mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: A1BG AK2 CRYL1 FURIN NR4A1	10 interactors: ABCC6 ANXA7 CDKN1A CRISP3 GRB7 PRDX4 SETD7 SMN1 SNCA TK1
Entrez ID		368	1
HPRD ID		04453	00726
Ensembl ID		ENSG00000091262	ENSG00000121410
Uniprot IDs		A2RRN8 O95255	P04217
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Nerve Growth Factor Production Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Receptor Catabolic Process Nerve Growth Factor Processing Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Production ADP Biosynthetic Process Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity DATP Metabolic Process Negative Regulation Of Proteolysis Nucleoside Diphosphate Biosynthetic Process Viral Protein Processing Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing ADP Metabolic Process Positive Regulation Of Membrane Protein Ectodomain Proteolysis Peptidyl-glutamic Acid Carboxylation Regulation Of Peptidase Activity AMP Metabolic Process Endothelial Cell Chemotaxis Response To Thyroid Hormone Nucleobase-containing Small Molecule Interconversion Signal Peptide Processing Cell Migration Involved In Sprouting Angiogenesis Virion Assembly Deoxyribonucleoside Triphosphate Metabolic Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Peptide Biosynthetic Process Blood Vessel Endothelial Cell Migration Regulation Of Proteolysis Peptide Hormone Processing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Catalytic Activity Response To Organic Substance	Response To Copper Ion Response To Metal Ion Response To Organic Cyclic Compound Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Male Germ Cell Proliferation Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Fetal Process Involved In Parturition Response To Stimulus Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Inorganic Substance Skeletal Muscle Cell Proliferation Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Response To Drug Response To Stress Regulation Of Male Germ Cell Proliferation Negative Regulation Of Dopamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Cellular Respiration Digestive Tract Development Negative Regulation Of Gene Expression Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Digestive System Development Regulation Of Reactive Oxygen Species Metabolic Process Response To Glucocorticoid Intestinal Epithelial Cell Maturation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Corticosteroid Ribonucleoprotein Complex Assembly Peptidyl-lysine Monomethylation Response To Iron(II) Ion Cellular Response To Copper Ion Response To Cortisol Thymidine Metabolic Process Response To Toxic Substance Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Synaptic Vesicle Recycling Deoxyribonucleoside Monophosphate Biosynthetic Process Cellular Response To UV-B Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Tagcloud ?		alpl bmp2 bmps calcification comes ectonucleotides elasticum enpp1 extrapolate localizing mineralisation mineralization msx2 multisystem neovascularisation osteoinductive papular perturbed pseudoxanthoma pxe runx2 smad2 smads stains subretinal tgfbeta tgfbeta1 tgfbetas whiskers	a2gl aiming apoa1 apoh apolipoprotein asses c1r c4 clus co4b crohn densitometrical glycoprotein ifx infliximab innovative offering plmn pnr pnrs proteomics rm rs serological serotransferrin subcomponent technologies trfe vtdb
Tagcloud (Difference) ?		alpl bmp2 bmps calcification comes ectonucleotides elasticum enpp1 extrapolate localizing mineralisation mineralization msx2 multisystem neovascularisation osteoinductive papular perturbed pseudoxanthoma pxe runx2 smad2 smads stains subretinal tgfbeta tgfbeta1 tgfbetas whiskers	a2gl aiming apoa1 apoh apolipoprotein asses c1r c4 clus co4b crohn densitometrical glycoprotein ifx infliximab innovative offering plmn pnr pnrs proteomics rm rs serological serotransferrin subcomponent technologies trfe vtdb
Tagcloud (Intersection) ?