A1BG and MTX1

Number of citations: 114 (PubMedID 34037656)
Data Source: BioGRID (pull down)

		A1BG	MTX1
Name		alpha-1-B glycoprotein	metaxin 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Platelet Alpha Granule Lumen Secretory Granule Lumen Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen	SAM Complex Mitochondrion Mitochondrial Outer Membrane Membrane MIB Complex
	Molecular Function	None	Protein Binding
	Biological Process	Immune Response-regulating Signaling Pathway	Mitochondrion Organization Inner Mitochondrial Membrane Organization Lactation Protein Transport Protein Insertion Into Mitochondrial Outer Membrane
Pathways		Platelet degranulation Neutrophil degranulation	Mitochondrial protein import Cristae formation RAC2 GTPase cycle
Drugs		Zinc Copper Zinc acetate	None
GWAS		No GWAS studies recorded	Blood urea nitrogen levels ( 31152163 ) Body fat distribution (leg fat ratio) ( 30664634 ) Body fat distribution (trunk fat ratio) ( 30664634 ) Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cancer ( 27197191 ) Cancer (pleiotropy) ( 27197191 ) Cortical surface area (min-P) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Cortical thickness (min-P) ( 32665545 ) Cortical thickness (MOSTest) ( 32665545 ) Crohn's disease ( 28067908 ) Estimated glomerular filtration rate ( 31451708 31015462 ) Gastric adenocarcinoma (histologically verified) ( 26098866 ) Gastric cancer ( 26098866 ) General risk tolerance (MTAG) ( 30643258 ) Gout ( 33832965 ) Hematocrit ( 27863252 32888494 ) Hemoglobin ( 32888494 ) Hemoglobin concentration ( 27863252 ) Hemoglobin levels ( 32327693 ) Inflammatory bowel disease ( 28067908 ) Low density lipoprotein cholesterol levels ( 32154731 ) Red blood cell count ( 27863252 32888494 ) Renal function-related traits (BUN) ( 22797727 ) Serum cancer antigen 15.3 levels ( 31666285 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 ) Urate levels ( 31578528 ) Urea levels ( 28270201 )
Interacting Genes		13 interacting genes: ABCC6 ANXA7 CDKN1A CRISP3 GRB7 HSP90AA1 MTX1 PRDX4 SAMM50 SETD7 SMN1 SNCA TK1	7 interacting genes: A1BG CLN8 GABARAP MAP1LC3A MAP1LC3B MTX2 TOMM40
Entrez ID		1	4580
HPRD ID		00726	11861
Ensembl ID		ENSG00000121410	ENSG00000173171
Uniprot IDs		P04217	Q13505
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Establishment Of Protein Localization To Mitochondrion SAM Complex MIB Complex Protein Insertion Into Mitochondrial Outer Membrane Response To Magnesium Ion Mitochondrial Membrane Organization Establishment Of Protein Localization To Organelle Protein Import Into Mitochondrial Matrix Protein Insertion Into Mitochondrial Membrane Establishment Of Protein Localization To Mitochondrial Membrane Protein Kinase Inhibitor Activity Protein Sequestering Activity Response To Cocaine Protein Localization To Mitochondrion Tau Protein Binding Inner Mitochondrial Membrane Organization Mitochondrial Outer Membrane CTP Binding DATP Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Mitochondrion Organization Membrane Organization Response To Xenobiotic Stimulus Positive Regulation Of Reactive Oxygen Species Metabolic Process PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Identical Protein Binding Protein Transmembrane Transport Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Protein Insertion Into Membrane Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Thymidine Kinase Activity Response To Metal Ion Regulation Of DNA Biosynthetic Process Response To Alkaloid DNA Biosynthetic Process Rho GDP-dissociation Inhibitor Binding Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Protein Tetramerization Negative Regulation Of Chaperone-mediated Autophagy DNA Synthesis Involved In Mitotic DNA Replication	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Vacuole Organization Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome Ceramide Binding Autophagosome Assembly Autophagosome Organization Mitochondrial Membrane Organization Protein Insertion Into Mitochondrial Outer Membrane Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Cellular Response To Starvation Organelle Organization Protein Insertion Into Mitochondrial Membrane Establishment Of Protein Localization To Mitochondrial Membrane Response To Starvation Mitochondrion Organization Microtubule Binding Cellular Response To Nutrient Levels Endomembrane System Organelle Membrane Autophagy Ubiquitin Protein Ligase Binding Microtubule Protein Insertion Into Membrane Establishment Of Protein Localization To Mitochondrion Response To Nutrient Levels Somatic Motor Neuron Differentiation Glutamate Reuptake Retinal Rod Cell Apoptotic Process Axoneme Positive Regulation Of Protein K48-linked Ubiquitination Cellular Response To Oxygen-glucose Deprivation Membrane Organization Mitochondrion Organelle Assembly Porin Activity Regulation Of Protein K48-linked Ubiquitination Retinal Cell Apoptotic Process Protein Targeting TOM Complex Mitochondrial Outer Membrane Response To Iron(II) Ion Establishment Of Protein Localization To Membrane Mitochondrial Outer Membrane Translocase Complex