TNFRSF9 and LRR1

Number of citations of the paper that reports this interaction (PMID 11804328)
5

Data Source:
HPRD (in vitro, two hybrid)

		TNFRSF9	LRR1
Gene Name		tumor necrosis factor receptor superfamily, member 9	leucine rich repeat protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Receptor Activity Cytokine Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Proliferation Protein Homotrimerization Negative Regulation Of Interleukin-10 Secretion Negative Regulation Of Interleukin-12 Secretion	Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		6 interactors: LRR1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3	4 interactors: MTUS2 PNMA2 TNFRSF9 TRIP13
Entrez ID		3604	122769
HPRD ID		03767	15164
Ensembl ID			ENSG00000165501
Uniprot IDs		Q07011	Q6AWA7 Q96L50
PDB IDs
Enriched GO Terms of Interacting Partners?		Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Programmed Cell Death Cell Death Death Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor Regulation Of Immunoglobulin Secretion Regulation Of Cytokine Production Positive Regulation Of Immune System Process Positive Regulation Of Cell Activation Apoptotic Process Regulation Of Lymphocyte Activation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune Response Regulation Of Immune System Process Cytokine-mediated Signaling Pathway Regulation Of Cell Activation Toll-like Receptor 4 Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Death Protein Ubiquitination Cellular Response To Cytokine Stimulus Toll-like Receptor Signaling Pathway Protein Modification By Small Protein Conjugation Positive Regulation Of Lymphocyte Proliferation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To Cytokine Positive Regulation Of Cytotoxic T Cell Differentiation Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Immune System Process Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Cytokine Production Positive Regulation Of T Cell Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Immunoglobulin Secretion Regulation Of T Cell Activation Positive Regulation Of Protein Homodimerization Activity Signal Transduction	Negative Regulation Of Interleukin-12 Secretion Regulation Of Interleukin-12 Secretion Negative Regulation Of Interleukin-10 Secretion Female Meiosis I Negative Regulation Of Interleukin-10 Production Protein Homotrimerization Regulation Of Interleukin-10 Secretion Negative Regulation Of Interleukin-12 Production Synaptonemal Complex Assembly Synaptonemal Complex Organization Oocyte Maturation Male Meiosis I Protein Trimerization Negative Regulation Of Cytokine Secretion Female Meiotic Division Reciprocal Meiotic Recombination Oocyte Development Oocyte Differentiation Synapsis Homologous Chromosome Segregation Male Meiosis Regulation Of Interleukin-12 Production
Tagcloud ?		ab block bmp brc differ downregulated estradiol estrogen ethanol ft4 highlights hydroxytamoxifen interfere menopausal modulated mu pgr plus postmenopausal progesterone tgfa tgfb1 thra thyroid tpo triiodothyronine tsh upregulated verified	autodock dap diaminopimelic docking executed flexx glide glutamyl hex ie injecting labeo lrr3 lrr8 mdap meso microbes motifs nod1 patchdock polycytidylic polyinosinic qrt recognizes rick rohita rohu servers
Tagcloud (Difference) ?		ab block bmp brc differ downregulated estradiol estrogen ethanol ft4 highlights hydroxytamoxifen interfere menopausal modulated mu pgr plus postmenopausal progesterone tgfa tgfb1 thra thyroid tpo triiodothyronine tsh upregulated verified	autodock dap diaminopimelic docking executed flexx glide glutamyl hex ie injecting labeo lrr3 lrr8 mdap meso microbes motifs nod1 patchdock polycytidylic polyinosinic qrt recognizes rick rohita rohu servers
Tagcloud (Intersection) ?