LRR1 and TNFRSF9

Number of citations of the paper that reports this interaction (PMID 11804328)
5

Data Source:
HPRD (in vitro, two hybrid)

		LRR1	TNFRSF9
Gene Name		leucine rich repeat protein 1	tumor necrosis factor receptor superfamily, member 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Extracellular Space Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function		Receptor Activity Cytokine Binding
	Biological Process	Protein Ubiquitination	Apoptotic Process Negative Regulation Of Cell Proliferation Protein Homotrimerization Negative Regulation Of Interleukin-10 Secretion Negative Regulation Of Interleukin-12 Secretion
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Celiac disease ( 20190752) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		4 interactors: MTUS2 PNMA2 TNFRSF9 TRIP13	6 interactors: LRR1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3
Entrez ID		122769	3604
HPRD ID		15164	03767
Ensembl ID		ENSG00000165501
Uniprot IDs		Q6AWA7 Q96L50	Q07011
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-12 Secretion Regulation Of Interleukin-12 Secretion Negative Regulation Of Interleukin-10 Secretion Female Meiosis I Negative Regulation Of Interleukin-10 Production Protein Homotrimerization Regulation Of Interleukin-10 Secretion Negative Regulation Of Interleukin-12 Production Synaptonemal Complex Assembly Synaptonemal Complex Organization Oocyte Maturation Male Meiosis I Protein Trimerization Negative Regulation Of Cytokine Secretion Female Meiotic Division Reciprocal Meiotic Recombination Oocyte Development Oocyte Differentiation Synapsis Homologous Chromosome Segregation Male Meiosis Regulation Of Interleukin-12 Production	Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Programmed Cell Death Cell Death Death Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor Regulation Of Immunoglobulin Secretion Regulation Of Cytokine Production Positive Regulation Of Immune System Process Positive Regulation Of Cell Activation Apoptotic Process Regulation Of Lymphocyte Activation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune Response Regulation Of Immune System Process Cytokine-mediated Signaling Pathway Regulation Of Cell Activation Toll-like Receptor 4 Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Death Protein Ubiquitination Cellular Response To Cytokine Stimulus Toll-like Receptor Signaling Pathway Protein Modification By Small Protein Conjugation Positive Regulation Of Lymphocyte Proliferation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To Cytokine Positive Regulation Of Cytotoxic T Cell Differentiation Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Immune System Process Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Cytokine Production Positive Regulation Of T Cell Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Immunoglobulin Secretion Regulation Of T Cell Activation Positive Regulation Of Protein Homodimerization Activity Signal Transduction
Tagcloud ?		autodock dap diaminopimelic docking executed flexx glide glutamyl hex ie injecting labeo lrr3 lrr8 mdap meso microbes motifs nod1 patchdock polycytidylic polyinosinic qrt recognizes rick rohita rohu servers	ab block bmp brc differ downregulated estradiol estrogen ethanol ft4 highlights hydroxytamoxifen interfere menopausal modulated mu pgr plus postmenopausal progesterone tgfa tgfb1 thra thyroid tpo triiodothyronine tsh upregulated verified
Tagcloud (Difference) ?		autodock dap diaminopimelic docking executed flexx glide glutamyl hex ie injecting labeo lrr3 lrr8 mdap meso microbes motifs nod1 patchdock polycytidylic polyinosinic qrt recognizes rick rohita rohu servers	ab block bmp brc differ downregulated estradiol estrogen ethanol ft4 highlights hydroxytamoxifen interfere menopausal modulated mu pgr plus postmenopausal progesterone tgfa tgfb1 thra thyroid tpo triiodothyronine tsh upregulated verified
Tagcloud (Intersection) ?