FAM101B and TNFRSF10C

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FAM101B	TNFRSF10C
Gene Name		family with sequence similarity 101, member B	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton	Integral Component Of Plasma Membrane Anchored Component Of Membrane
	Molecular Function	Filamin Binding	Transmembrane Signaling Receptor Activity TRAIL Binding
	Biological Process	Epithelial To Mesenchymal Transition Actin Cytoskeleton Organization	Apoptotic Process Signal Transduction
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: KAT5 PPP1R16A TNFRSF10C ZBTB16	9 interactors: APOA1 FAM101B LRSAM1 RAP1A SLC27A6 SRPK1 SRPK2 TNFSF10 ZHX1
Entrez ID		359845	8794
HPRD ID		14646	04681
Ensembl ID		ENSG00000183688	ENSG00000173535
Uniprot IDs		Q8N5W9	O14798
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NK T Cell Differentiation Male Germ-line Stem Cell Asymmetric Division DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Cellular Response To Estradiol Stimulus Negative Regulation Of Interleukin-2 Production Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Acetylation Cellular Response To Estrogen Stimulus Positive Regulation Of Chondrocyte Differentiation Apoptotic Process Androgen Receptor Signaling Pathway Programmed Cell Death Stem Cell Division Positive Regulation Of Alpha-beta T Cell Differentiation Positive Regulation Of Cartilage Development Cell Death Death Negative Regulation Of Transcription, DNA-templated Embryonic Hindlimb Morphogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Forelimb Morphogenesis Positive Regulation Of Fat Cell Differentiation Hindlimb Morphogenesis Regulation Of Chondrocyte Differentiation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Intracellular Steroid Hormone Receptor Signaling Pathway Embryonic Digit Morphogenesis Negative Regulation Of Biosynthetic Process	Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Transport Negative Regulation Of Viral Process Negative Regulation Of Cell Adhesion Molecule Production Nuclear Speck Organization Ubiquitin-dependent Endocytosis Regulation Of MRNA Processing Cell Differentiation Regulation Of RNA Splicing Negative Regulation Of Interleukin-1 Beta Secretion Developmental Process Nucleus Organization Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Negative Regulation Of Interleukin-1 Secretion Regulation Of Viral Process Negative Regulation Of Secretion By Cell Negative Regulation Of Secretion High-density Lipoprotein Particle Clearance Platelet Activation Protein Oxidation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Heterotypic Cell-cell Adhesion Negative Regulation Of Cytokine Secretion Involved In Immune Response High-density Lipoprotein Particle Assembly Cell Development Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Cholesterol Esterification Sperm Chromatin Condensation Viral Budding Regulation Of Intestinal Cholesterol Absorption Rap Protein Signal Transduction Phospholipid Homeostasis Peptidyl-methionine Modification Anatomical Structure Development Regulation Of Cellular Component Organization Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Vasculogenesis Phospholipid Efflux Nerve Growth Factor Signaling Pathway Regulation Of Cytokine Secretion Involved In Immune Response Lipid Transport Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity
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