IGLL1 and FAM25C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IGLL1	FAM25C
Description		immunoglobulin lambda like polypeptide 1	family with sequence similarity 25 member C
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Membrane IgG Immunoglobulin Complex
	Molecular Function	Antigen Binding Protein Binding
	Biological Process	Immune Response Immunoglobulin Mediated Immune Response
Pathways		Cell surface interactions at the vascular wall
Drugs		Copper
Diseases		Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Blood protein levels ( 30072576) Height ( 18391951) HOMA-B (corrected for HOMA-IR) ( 30369944) Migraine ( 21448238) Peripheral artery disease ( 25009551)	Pancreas fat ( 34128465)
Interacting Genes		6 interacting genes: FAM25A FAM25C FAM25G FAT1 MYOC UBQLN2	18 interacting genes: ARMC10 ARMCX3 COX16 GPD1 IGLL1 KLHL35 LCN1 LCN2 MIEF1 MIEF2 PPIC PPIF S100A6 SNX1 TDRKH TOMM20L TTPA ZFAND3
Entrez ID		3543	644054
HPRD ID		00905	19638
Ensembl ID		ENSG00000128322	ENSG00000276430
Uniprot IDs		P15814	B3EWG5
PDB IDs		2H32 2H3N 2LKQ
Enriched GO Terms of Interacting Partners?			Mitochondrial Outer Membrane Cyclosporin A Binding Regulation Of Mitochondrion Organization Mitochondrion Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Small Molecule Binding Positive Regulation Of Protein Targeting To Membrane Regulation Of Mitochondrial Fission Regulation Of Protein Targeting To Membrane Peptidyl-prolyl Cis-trans Isomerase Activity Glycerol-3-phosphate Dehydrogenase (NAD+) Activity Positive Regulation Of Hippocampal Neuron Apoptotic Process Negative Regulation Of Establishment Of Blood-brain Barrier Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Glycerol-3-phosphate Dehydrogenase [NAD(P)+] Activity Glycerol-3-phosphate Catabolic Process Glycerol-3-phosphate Shuttle Positive Regulation Of Iron Ion Import Across Plasma Membrane Enterobactin Binding Positive Regulation Of Endothelial Tube Morphogenesis Iron Ion Sequestering Activity Positive Regulation Of Growth Rate TRNA Import Into Mitochondrion Cellular Response To Hydrogen Peroxide
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