KRTAP12-1 and PDIA4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP12-1	PDIA4
Description		keratin associated protein 12-1	protein disulfide isomerase family A member 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cell Surface Melanosome
	Molecular Function	Protein Binding	RNA Binding Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Isomerase Activity
	Biological Process		Protein Folding Protein Secretion Response To Endoplasmic Reticulum Stress
Pathways		Keratinization
Drugs
Diseases
GWAS			Height ( 20881960) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		62 interacting genes: CATSPER1 CHRD CYSRT1 DHRS1 ENKD1 FHL3 GATA3 GPRIN2 GRN HOXA1 HOXC8 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-2 KRTAP4-4 KRTAP4-5 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE3A LCE5A MEOX2 MGAT5B NBPF19 NEU4 NOTCH2NLA OTX1 PDIA2 PDIA4 PEF1 POU2AF1 POU4F2 PRR35 RBPMS SMCP TOX TRIP13 UBQLN2 VGLL3 ZIC1	7 interacting genes: APOB BCL2L1 CEBPA GADD45G KRTAP10-8 KRTAP12-1 LCN2
Entrez ID		353332	9601
HPRD ID		11197	06501
Ensembl ID		ENSG00000187175	ENSG00000155660
Uniprot IDs		P59990	A0A090N8Y2 A0A499FI48 P13667
PDB IDs			3IDV
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Protein Binding	Mature Chylomicron Sterol Metabolic Process Response To Virus Cholesterol Metabolic Process Cellular Response To Amyloid-beta Response To Amyloid-beta Chylomicron Remnant Positive Regulation Of Programmed Cell Death Response To Amino Acid Extrinsic Apoptotic Signaling Pathway Response To Peptide Positive Regulation Of Apoptotic Process Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Response To Cytokine Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Response To Ionizing Radiation Apoptotic Process In Bone Marrow Cell Acute-phase Response CHOP-C/EBP Complex Response To Tumor Necrosis Factor Cellular Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 Memory C/EBP Complex Acute Inflammatory Response Positive Regulation Of Iron Ion Import Across Plasma Membrane Positive Regulation Of Hippocampal Neuron Apoptotic Process Siderophore Transport Enterobactin Binding Positive Regulation Of Endothelial Tube Morphogenesis Iron Ion Sequestering Activity Positive Regulation Of Cold-induced Thermogenesis Keratin Filament Fertilization Triglyceride Mobilization Response To Ionizing Radiation White Fat Cell Proliferation Cytoplasmic Vesicle Lumen Regulation Of Cold-induced Thermogenesis Negative Regulation Of Hippocampal Neuron Apoptotic Process Response To Kainic Acid Lipid Homeostasis Intermediate-density Lipoprotein Particle Response To Cycloheximide Cellular Response To Radiation Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex
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