TBC1D26 and SRRM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TBC1D26	SRRM4
Description		TBC1 domain family member 26	serine/arginine repetitive matrix 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus
	Molecular Function	GTPase Activator Activity	RNA Binding MRNA Binding Protein Binding Identical Protein Binding
	Biological Process		Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development Sensory Perception Of Sound RNA Splicing Cell Differentiation Neuron Maturation Regulation Of RNA Splicing
Pathways
Drugs
Diseases
GWAS			Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Facial morphology (factor 3, length of philtrum) ( 28441456) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Photic sneeze reflex ( 27182965) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Stroke ( 32693751)
Interacting Genes		12 interacting genes: APP BYSL CARD10 HOXB5 KRTAP10-9 PICK1 RNPS1 SRRM4 TRIM41 TSPYL2 ZNF587 ZNF792	34 interacting genes: - AKAP17A ARL6IP4 C16orf87 C1orf35 CACNA1A CDC37 CLK1 CLK4 FAM9B LUC7L LUC7L2 LUZP4 MCRS1 PRPF38A RBM25 RBM39 RBMX2 RNPS1 RSRC1 SNIP1 SNRNP70 SREK1 SRRM1 SRSF11 SRSF4 TBC1D26 U2AF1 WDR5 ZNF124 ZNF286A ZNF699 ZRSR2 ZRSR2P1
Entrez ID		353149	84530
HPRD ID		14670	13897
Ensembl ID		ENSG00000214946	ENSG00000139767
Uniprot IDs		A0A8J8ZQP4 Q86UD7	A7MD48 V5T9A0
PDB IDs
Enriched GO Terms of Interacting Partners?			RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions Nuclear Speck Spliceosomal Complex RNA Binding MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Metabolic Process Nucleic Acid Binding Nucleic Acid Metabolic Process Nucleus Regulation Of MRNA Splicing, Via Spliceosome Pre-mRNA 3'-splice Site Binding RS Domain Binding U2AF Complex Regulation Of MRNA Processing Nucleobase-containing Compound Metabolic Process U2-type Prespliceosome U1 SnRNP MRNA Binding Regulation Of MRNA Metabolic Process Protein-RNA Complex Assembly U1 SnRNP Binding Spliceosomal Complex Assembly U2-type Precatalytic Spliceosome NSL Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleoplasm Precatalytic Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Histone Acetyltransferase Complex U2-type Prespliceosome Assembly Negative Regulation Of RNA Splicing U2 SnRNP Protein Serine/threonine/tyrosine Kinase Activity MLL1 Complex Histone H3Q5ser Reader Activity MRNA Splice Site Recognition Macromolecule Metabolic Process Negative Regulation Of Protein Refolding Histone H3K4me1 Reader Activity HSP90-CDC37 Chaperone Complex
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