LCE1A and KRTAP3-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCE1A	KRTAP3-2
Description		late cornified envelope 1A	keratin associated protein 3-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Epidermis Development Keratinization
Pathways		Formation of the cornified envelope	Keratinization
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		83 interacting genes: ADAMTSL4 AQP1 CCN3 CFP CHIC2 CRCT1 CYSRT1 EFEMP2 FBLN1 FUCA2 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A LCE5A MACO1 MDFI MESD NBPF19 NID2 NOTCH2NLA PLA2G10 PLAC8 PLSCR2 PLSCR4 RGS17 RGS20 SLC39A7 SMCP SPRY1 SPRY2 SPRY3 TGFB1 TRIM42 TSPAN4 VASN VWC2 VWC2L	75 interacting genes: ADAM12 ADAMTSL3 AQP1 ARFGAP1 ATG9A CATSPER1 CCDC28A-AS1 CELF5 CERK CNNM3 COL8A1 CREB5 DHRS1 DUSP10 EFEMP2 FOXD2 FRS3 GAD1 GARIN6 GATA1 GUCD1 HOXA1 HOXB9 HYAL2 HYPK ITGB5 KIF25-AS1 KPRP KRTAP10-1 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-12 KRTAP4-4 KRTAP9-2 KRTAP9-3 LASP1 LCE1A LCE1B LCE1F LCE2A LCE3A LCE3C LCE3D LCE3E LCE4A MAN2B2 MAPKBP1 NR1D2 NTM NUFIP2 OLIG3 OTX1 PCSK5 PLSCR3 POGZ POU4F2 PRR34 R3HDM2 SAXO4 SLC13A5 SMARCC1 SPATA31J1 SPRY1 TBC1D16 TRIM42 TRIP13 VASN YIPF3 ZIC1 ZIM2
Entrez ID		353131	83897
HPRD ID		13966	13938
Ensembl ID		ENSG00000186844	ENSG00000212900
Uniprot IDs		Q5T7P2	Q9BYR7
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Protein Binding Identical Protein Binding Branch Elongation Of An Epithelium Axis Elongation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Ras Protein Signal Transduction Elastic Fiber Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Interstitial Matrix Regulation Of Lens Fiber Cell Differentiation	Intermediate Filament Keratinization Keratin Filament Epidermis Development Tissue Development Protein Binding
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