IGHD and BCAP31

Number of citations of the paper that reports this interaction (PubMedID 12886015)
48

Data Source:
HPRD (in vitro, in vivo)

		IGHD	BCAP31
Description		immunoglobulin heavy constant delta	B cell receptor associated protein 31
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Immunoglobulin Complex Immunoglobulin Complex, Circulating Extracellular Exosome IgD Immunoglobulin Complex Blood Microparticle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Perinuclear Endoplasmic Reticulum Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Antigen Binding Immunoglobulin Receptor Binding	Protein Binding MHC Class I Protein Binding Protein-containing Complex Binding
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Complement Activation, Classical Pathway Antibacterial Humoral Response Positive Regulation Of Interleukin-1 Production B Cell Receptor Signaling Pathway	Protein Targeting To Mitochondrion Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Spermatogenesis Protein Transport Vesicle-mediated Transport Response To Endoplasmic Reticulum Stress Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of ERAD Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Apoptotic cleavage of cellular proteins Apoptotic execution phase RHOA GTPase cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC RSV-host interactions
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: BCAP29 BCAP31	30 interacting genes: ACTG1 APP AQP2 BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 CDC42 CEBPA DRD2 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 MSN MYH10 PLP2 SERPINF2 TIMMDC1 TMEM31 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ
Entrez ID		3495	10134
HPRD ID		11823	02319
Ensembl ID		ENSG00000211898	ENSG00000185825
Uniprot IDs			P51572
PDB IDs			4JZL 4JZP 8XWX
Enriched GO Terms of Interacting Partners?		Protein Localization To Endoplasmic Reticulum Exit Site Protein Localization To Endoplasmic Reticulum Establishment Of Protein Localization To Mitochondrion Protein Localization To Organelle Cell Death Apoptotic Process CTP Binding DATP Binding Programmed Cell Death Positive Regulation Of Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Protein Transport Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Intracellular Transport Establishment Of Protein Localization Positive Regulation Of Protein Catabolic Process Rho GDP-dissociation Inhibitor Binding Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of Protein Transport Cellular Localization Regulation Of Intracellular Transport Establishment Of Localization In Cell Golgi Vesicle Transport Sperm Mitochondrial Sheath Positive Regulation Of Establishment Of Protein Localization Telomerase Holoenzyme Complex Assembly Intracellular Protein Localization Establishment Of Protein Localization To Organelle Chaperone-mediated Autophagy Nitric-oxide Synthase Regulator Activity Regulation Of Protein Catabolic Process Dendritic Growth Cone Sperm Plasma Membrane TPR Domain Binding Positive Regulation Of Cardiac Muscle Contraction Inclusion Body Assembly Positive Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Protein Transport Positive Regulation Of Protein Localization Positive Regulation Of Cell Size Protein Unfolding Cardiac Muscle Cell Apoptotic Process Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of Striated Muscle Contraction Striated Muscle Cell Apoptotic Process Enzyme-substrate Adaptor Activity	Response To Peptide Response To Cytokine Regulation Of Transport SNARE Complex Assembly Response To Metal Ion Cell Projection Morphogenesis Positive Regulation Of Gene Expression Axonogenesis Neuron Projection Morphogenesis Cellular Response To Type II Interferon Membrane Positive Regulation Of Interleukin-1 Production Regulation Of Defense Response Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of Inflammatory Response Regulation Of Body Fluid Levels Dendritic Cell Apoptotic Process Positive Regulation Of Inflammatory Response Membrane Organization Cellular Component Assembly Vesicle-mediated Transport Neuron Projection Positive Regulation Of Cytokine Production Response To Type II Interferon Mitochondrial Outer Membrane Regulation Of Vesicle-mediated Transport Protein-containing Complex SNAP Receptor Activity Regulation Of Immune System Process BH3 Domain Binding Response To Anesthetic Channel Activity Regulation Of Interleukin-1 Production Renal System Process Blood Microparticle Regulation Of Cytokine Production Response To Nicotine Pyroptotic Inflammatory Response Death-inducing Signaling Complex Regulation Of Histamine Secretion By Mast Cell Defense Response Cell Surface Receptor Signaling Pathway Macrophage Differentiation SNARE Complex Epithelial Cell Apoptotic Process Leukocyte Apoptotic Process Synaptic Vesicle Membrane Endocytosis Negative Regulation Of Dendritic Cell Apoptotic Process
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