BEX5 and COPS7B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BEX5	COPS7B
Description		brain expressed X-linked 5	COP9 signalosome subunit 7B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol COP9 Signalosome Protein-containing Complex
	Molecular Function	Signaling Receptor Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Signal Transduction	Protein Deneddylation COP9 Signalosome Assembly Regulation Of Protein Neddylation
Pathways			DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS			Height ( 18391951)
Interacting Genes		15 interacting genes: BFSP2 COPS7B CRK EMILIN1 FARS2 FOXD4L3 GNG13 GOLGA8F ING3 LSM1 MAGEA8 MORF4L1 MORF4L2 NDUFAB1 PACRGL	6 interacting genes: APP BEX5 EIF3E NMI PMF1 UBC
Entrez ID		340542	64708
HPRD ID		18484	09889
Ensembl ID		ENSG00000184515	ENSG00000144524
Uniprot IDs		Q5H9J7	A0A087X1P5 J3KQ34 J3KQ41 Q6ZTQ7 Q9H9Q2
PDB IDs			6R6H 6R7F 6R7H 6R7I 6R7N 8H38 8H3A 8H3F
Enriched GO Terms of Interacting Partners?		NuA4 Histone Acetyltransferase Complex Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA Recombination Positive Regulation Of Double-strand Break Repair Nucleosome Regulation Of DNA Recombination Positive Regulation Of DNA Repair Regulation Of Double-strand Break Repair	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Response To Calcium Ion Macrophage Activation Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Myeloid Leukocyte Activation Growth Factor Receptor Binding Main Axon Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Eukaryotic Translation Initiation Factor 3 Complex, EIF3e Negative Regulation Of Interferon-alpha Production Positive Regulation Of Protein K48-linked Ubiquitination MIS12/MIND Type Complex Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Protein Metabolic Process NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Protein K48-linked Ubiquitination Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion
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