ID4 and ID3

Number of citations of the paper that reports this interaction (PMID 8759016)
17

Data Source:
HPRD (in vivo, two hybrid)

		ID4	ID3
Gene Name		inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase II Transcription Factor Binding Transcription Corepressor Activity Protein Binding Protein Dimerization Activity	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Dimerization Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Neuroblast Proliferation Circadian Rhythm Positive Regulation Of Cell Proliferation Hippocampus Development Cerebral Cortex Neuron Differentiation Central Nervous System Myelination Cellular Protein Localization Fat Cell Differentiation Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Metanephros Development Regulation Of DNA Replication Transcription, DNA-templated Multicellular Organismal Development Central Nervous System Development Heart Development Muscle Organ Development Circadian Rhythm Response To Wounding Neuron Differentiation Epithelial Cell Differentiation Notochord Development Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Endometriosis ( 23472165) Height ( 20881960) Response to statin therapy ( 20339536)
Protein-Protein Interactions		4 interactors: HES1 ID3 MYOD1 TCF4	36 interactors: ADD1 ATF3 CBFA2T2 CDK2 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626
Entrez ID		3400	3399
HPRD ID		08995	02608
Ensembl ID			ENSG00000117318
Uniprot IDs		P47928	Q02535
PDB IDs			2LFH
Enriched GO Terms of Interacting Partners?		Muscle Structure Development Myoblast Fate Commitment Cell Fate Commitment Muscle Cell Differentiation Regulation Of Myoblast Differentiation Regulation Of Cell Differentiation Regulation Of Oligodendrocyte Differentiation Myoblast Differentiation Cell Fate Determination Tissue Development Pituitary Gland Development Embryonic Organ Development Positive Regulation Of Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Skeletal Muscle Tissue Development Somatic Stem Cell Maintenance Regulation Of Glial Cell Differentiation Regulation Of BMP Signaling Pathway Diencephalon Development Transcription, DNA-templated Pancreas Development RNA Biosynthetic Process Regulation Of Gliogenesis Negative Regulation Of Cell Differentiation Metanephros Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Binding Protein Import Into Nucleus Nuclear Import Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Regulation Of Fat Cell Differentiation Regulation Of Cell Development Positive Regulation Of Cell Differentiation Odontogenesis Transcription From RNA Polymerase II Promoter Regulation Of Striated Muscle Tissue Development Cardiovascular System Development Cellular Response To Starvation Regulation Of Cell Cycle Stem Cell Maintenance Regulation Of Muscle Cell Differentiation Protein Import Organ Development Central Nervous System Development Organ Morphogenesis Protein Localization To Nucleus	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Muscle Structure Development Skeletal Muscle Cell Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Fiber Development Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Cell Fate Commitment Negative Regulation Of Transcription From RNA Polymerase II Promoter Striated Muscle Tissue Development Multicellular Organismal Development Muscle Cell Differentiation Muscle Tissue Development Negative Regulation Of Cellular Metabolic Process Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Organ Development
Tagcloud ?		9a8 bodies concluded confined diffuse excess fixed frozen gn gs hcp hpi ica igg1 igg2a immunofluorescent indirect intense islet islets mab pancreas proinsulin radiating reacting sections staining treadlike visualized	accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Difference) ?		9a8 bodies concluded confined diffuse excess fixed frozen gn gs hcp hpi ica igg1 igg2a immunofluorescent indirect intense islet islets mab pancreas proinsulin radiating reacting sections staining treadlike visualized	accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Intersection) ?