PPM1J and CSN1S1

Number of citations of the paper that reports this interaction (PubMedID 12633878)
0

Data Source:
HPRD (in vitro)

		PPM1J	CSN1S1
Description		protein phosphatase, Mg2+/Mn2+ dependent 1J	casein alpha s1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Extracellular Region Extracellular Space
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (acetyl-transferring)]-phosphatase Activity Protein Binding Hydrolase Activity	Protein Binding
	Biological Process		Response To Estradiol Response To Progesterone Response To Dehydroepiandrosterone Response To 11-deoxycorticosterone
Pathways			Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronic kidney disease ( 31152163) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31015462 31152163 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: ADORA2A CSN1S1 F2RL1 GPR37 LGALS14 PLEKHN1 PTAFR SMARCD1 SPG21 SUMO1 UBE2I	11 interacting genes: CSNK2A1 CSNK2B HTRA2 PARK7 PLK1 PPM1J PRSS2 STK4 TOLLIP TTBK1 UBQLN2
Entrez ID		333926	1446
HPRD ID		15171	00280
Ensembl ID		ENSG00000155367	ENSG00000126545
Uniprot IDs		Q5JR12	P47710
PDB IDs
Enriched GO Terms of Interacting Partners?		Small Protein Activating Enzyme Binding Purinergic Nucleotide Receptor Signaling Pathway G Protein-coupled Receptor Activity Transcription Factor Binding Presynaptic Cytosol Postsynaptic Cytosol Vasodilation Response To 11-deoxycorticosterone Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Protein Sumoylation SUMO Conjugating Enzyme Activity Enzyme Binding Regulation Of Acetylcholine Secretion, Neurotransmission G Protein-coupled Receptor Signaling Pathway Coagulation Regulation Of Protein Transport Blood Coagulation Hemostasis Renal System Process Positive Regulation Of Acetylcholine Secretion, Neurotransmission Type 5 Metabotropic Glutamate Receptor Binding Response To Dehydroepiandrosterone Proteinase-activated Receptor Activity Positive Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Killing Of Cells Of Another Organism Prosaposin Receptor Activity Platelet Activating Factor Receptor Activity Inositol Trisphosphate Biosynthetic Process RING-like Zinc Finger Domain Binding SUMO Ligase Complex HLH Domain Binding PML Body Nuclear Pore Protein Localization To Nuclear Pore Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Negative Regulation Of Protein Transport	Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Regulation Of Protein Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Proteolysis Protein Serine/threonine Kinase Activity Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Autophagy Identical Protein Binding PML Body Protein Serine Kinase Activity Negative Regulation Of Protein Catabolic Process Regulation Of Protein Stability Regulation Of Autophagy Negative Regulation Of Catabolic Process Phosphorylation Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Proteolysis Regulation Of Protein Sumoylation Positive Regulation Of Apoptotic Signaling Pathway Execution Phase Of Apoptosis Protein Localization To Site Of Double-strand Break PcG Protein Complex Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Kinase Activity Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Macroautophagy Regulation Of Cellular Response To Stress Positive Regulation Of Protein Catabolic Process Positive Regulation Of Catabolic Process Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Peptidyl-serine Phosphorylation Macromolecule Metabolic Process Wnt Signaling Pathway Protein Localization To Organelle Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Growth Negative Regulation Of DNA Recombination Protein Stabilization Kinase Activity
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