HRC and TRDN

Number of citations of the paper that reports this interaction (PMID 11504710)
16

Data Source:
HPRD (in vitro, in vivo)

		HRC	TRDN
Gene Name		histidine rich calcium binding protein	triadin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Z Disc Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen	Cytoplasm Endoplasmic Reticulum Plasma Membrane Voltage-gated Calcium Channel Complex Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Calcium Channel Complex
	Molecular Function	Calcium Ion Binding Protein Binding Ion Channel Binding ATPase Binding	Receptor Binding Protein Binding Protein Binding, Bridging Protein Homodimerization Activity Ion Channel Binding
	Biological Process	Regulation Of Heart Rate Muscle Contraction Positive Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Heart Contraction Cytosolic Calcium Ion Homeostasis Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Relaxation Of Cardiac Muscle Regulation Of Calcium Ion Transmembrane Transport	Cellular Calcium Ion Homeostasis Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cytoplasmic Microtubule Organization Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transmembrane Transport Heart Contraction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Membrane Potential Endoplasmic Reticulum Membrane Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Pathways			Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: TRDN	5 interactors: ASPH CALM1 CASQ2 HRC RYR1
Entrez ID		3270	10345
HPRD ID		00818	04474
Ensembl ID		ENSG00000130528	ENSG00000186439
Uniprot IDs		P23327	H9ME53 Q13061 Q68D40 Q8IVK2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Endoplasmic Reticulum Membrane Organization Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cell Communication By Electrical Coupling Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Membrane Potential Negative Regulation Of Calcium Ion Transport Into Cytosol Sarcoplasmic Reticulum Calcium Ion Transport Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cell Communication By Electrical Coupling Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Cation Channel Activity Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Sequestering Of Calcium Ion Cytoplasmic Microtubule Organization Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Endoplasmic Reticulum Organization Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transporter Activity Negative Regulation Of Transmembrane Transport Positive Regulation Of Transporter Activity Myotube Differentiation Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Heart Contraction Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Regulation Of Calcium Ion Transport Into Cytosol Positive Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transport Negative Regulation Of Intracellular Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Cytosolic Calcium Ion Homeostasis Regulation Of Calcium Ion Transport Positive Regulation Of Ion Transport	Regulation Of Cell Communication By Electrical Coupling Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Ion Homeostasis Muscle Contraction Muscle System Process Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cation Channel Activity Regulation Of Cardiac Muscle Contraction Regulation Of Calcium Ion Transport Into Cytosol Detection Of Calcium Ion Regulation Of Striated Muscle Contraction Calcium-mediated Signaling Regulation Of Ion Transmembrane Transport Second-messenger-mediated Signaling Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of Ion Transport Regulation Of Calcium Ion Transport Regulation Of Heart Rate Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Intracellular Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Response To Calcium Ion Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Caffeine Response To Purine-containing Compound Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity Response To Organonitrogen Compound Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Response To Organic Cyclic Compound Response To Caffeine Regulation Of Cellular Localization Positive Regulation Of Cation Channel Activity Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Response To Metal Ion Cellular Response To Alkaloid Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transmembrane Transport Detection Of Chemical Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity
Tagcloud ?		aerial albus bacillus chaperones circe complemented differently dnak groe groel1 groel2 groes grpe heat homologs hrca hsp18 hspr mycelium operator operon orfy repressors shock sporulation stands stimulon streptomyces subtilis
Tagcloud (Difference) ?		aerial albus bacillus chaperones circe complemented differently dnak groe groel1 groel2 groes grpe heat homologs hrca hsp18 hspr mycelium operator operon orfy repressors shock sporulation stands stimulon streptomyces subtilis
Tagcloud (Intersection) ?