HOXC11 and TBX21

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HOXC11	TBX21
Gene Name		homeobox C11	T-box 21
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Neuronal Cell Body
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription	Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding
	Biological Process	Metanephros Development Organ Induction Transcription, DNA-templated Endoderm Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Digit Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal Joint Morphogenesis	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Response To Virus T Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Isotype Switching To IgG Isotypes Cellular Response To Organic Substance Lymphocyte Migration
Pathways
Drugs
Diseases
GWAS			Multiple sclerosis ( 22190364)
Protein-Protein Interactions		12 interactors: CD2AP GTF2A1L GTF2H1 HDAC5 HTT IRF4 MEIS1 SMAD3 SOX8 SP1 STAT3 TBX21	3 interactors: EXOC5 HOXC11 ZNF490
Entrez ID		3227	30009
HPRD ID		09275	05355
Ensembl ID		ENSG00000123388	ENSG00000073861
Uniprot IDs		O43248	Q9UL17
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Heterocycle Metabolic Process Biosynthetic Process Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Immune System Development Negative Regulation Of Cell Differentiation Eye Development Eye Morphogenesis Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Organ Development Regulation Of Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mesenchyme Development Regulation Of RNA Metabolic Process Regulation Of Cell Differentiation Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Cell Differentiation Organ Morphogenesis Cellular Aromatic Compound Metabolic Process Sensory Organ Development Regulation Of Nitrogen Compound Metabolic Process Ossification Hemopoiesis Negative Regulation Of Neurogenesis Cellular Response To Organic Substance Negative Regulation Of Cell Development Paraxial Mesoderm Morphogenesis System Development Camera-type Eye Development Regulation Of Metabolic Process Camera-type Eye Morphogenesis
Tagcloud ?		absent akt1 colinearly demethylating evolutionarily fibroblast h3k27me3 h3k9 hdac hdac6 hoxc5 hoxd10 interacted kdm6b mark mef organized patterning posterior reagent repressed silico specify synergistically tss turned	1514t 1993t acc additive associate atc bet box china chinese clinicopathological coming counted distant escc esophagus haplotypes influential inherited log node ors pivotal polarization polymorphisms restriction rflp th1 th2
Tagcloud (Difference) ?		absent akt1 colinearly demethylating evolutionarily fibroblast h3k27me3 h3k9 hdac hdac6 hoxc5 hoxd10 interacted kdm6b mark mef organized patterning posterior reagent repressed silico specify synergistically tss turned	1514t 1993t acc additive associate atc bet box china chinese clinicopathological coming counted distant escc esophagus haplotypes influential inherited log node ors pivotal polarization polymorphisms restriction rflp th1 th2
Tagcloud (Intersection) ?