HOXC10 and NUP205

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HOXC10	NUP205
Gene Name		homeobox C10	nucleoporin 205kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex	Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Membrane Nuclear Membrane Nuclear Periphery
	Molecular Function	Sequence-specific DNA Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Skeletal System Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Spinal Cord Motor Neuron Cell Fate Specification Embryonic Limb Morphogenesis Neuromuscular Process	Protein Import Into Nucleus, Docking Mitotic Cell Cycle Carbohydrate Metabolic Process Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Nuclear Pore Complex Assembly Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS			Paget's disease ( 21623375)
Protein-Protein Interactions		4 interactors: CDC27 EGFR NUP205 YWHAG	2 interactors: HOXC10 NUP93
Entrez ID		3226	23165
HPRD ID		05710	17653
Ensembl ID		ENSG00000180818	ENSG00000155561
Uniprot IDs		Q53XI4 Q9NYD6	Q92621
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Negative Regulation Of Protein Catabolic Process Alkanesulfonate Metabolic Process Membrane Organization Negative Regulation Of Protein Metabolic Process Protein Import Into Nucleus, Docking Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Intracellular Transport Activation Of Phospholipase A2 Activity Cellular Protein Localization Positive Regulation Of Phospholipase A2 Activity Establishment Of Protein Localization Response To Cobalamin Response To UV-A Negative Regulation Of Transferase Activity Regulation Of Synaptic Transmission Nuclear Pore Complex Assembly Response To Hydroxyisoflavone Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Metaphase/anaphase Transition Of Mitotic Cell Cycle Nuclear Pore Organization Regulation Of Protein Catabolic Process Positive Regulation Of Catenin Import Into Nucleus Regulation Of Mitotic Cell Cycle Protein Targeting Cellular Response To Organic Substance Pore Complex Assembly Regulation Of Phospholipase A2 Activity Regulation Of Intracellular Transport Protein Localization Regulation Of Superoxide Anion Generation Negative Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Cellular Response To Organonitrogen Compound Magnesium Ion Homeostasis Regulation Of Protein Metabolic Process Cellular Response To Estradiol Stimulus Positive Regulation Of Transferase Activity Cellular Response To Hormone Stimulus Protein Insertion Into Membrane Astrocyte Development Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity	Nuclear Pore Complex Assembly Nuclear Pore Organization Poly(A)+ MRNA Export From Nucleus Pore Complex Assembly Spinal Cord Motor Neuron Cell Fate Specification Neuron Fate Specification Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Spinal Cord Motor Neuron Differentiation Proximal/distal Pattern Formation Ventral Spinal Cord Development Cell Differentiation In Spinal Cord Nuclear Envelope Organization MRNA Export From Nucleus Glucose Transport RNA Export From Nucleus Hexose Transport Neuron Fate Commitment Viral Transcription Cell Fate Specification Regulation Of Glucose Transport Spinal Cord Development Nuclear Export MRNA Transport Protein Import Into Nucleus Nucleus Organization RNA Biosynthetic Process Nuclear Import Carbohydrate Transport Neuromuscular Process RNA Transport RNA Localization Protein Import Embryonic Limb Morphogenesis Protein Localization To Nucleus Limb Morphogenesis Viral Life Cycle
Tagcloud ?		ai ais antiestrogen aromatase blockade concurrent confers contributing cpg delaying enrichment h3k27me3 homeobox hyper hypermethylation hypomethylation overlapped paired permanent recurred relief represses repression shore supporting transitioning ultimately widespread xenografts
Tagcloud (Difference) ?		ai ais antiestrogen aromatase blockade concurrent confers contributing cpg delaying enrichment h3k27me3 homeobox hyper hypermethylation hypomethylation overlapped paired permanent recurred relief represses repression shore supporting transitioning ultimately widespread xenografts
Tagcloud (Intersection) ?