HOXA7 and JUNB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HOXA7	JUNB
Gene Name		homeobox A7	jun B proto-oncogene
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Chromatin Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Factor Binding Sequence-specific DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Angiogenesis Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Leukocyte Migration Transcription, DNA-templated Anterior/posterior Pattern Specification Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of Monocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Stem Cell Differentiation	Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Response To Light Stimulus Response To Mechanical Stimulus Gene Expression Osteoclast Differentiation Response To Progesterone Cellular Response To Hormone Stimulus Osteoblast Proliferation Response To Cytokine Response To Drug Response To Peptide Hormone Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Decidualization Response To Corticosterone Response To CAMP Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			Loss of Function of TGFBR2 in Cancer TGFBR2 MSI Frameshift Mutants in Cancer SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer SMAD2/3 MH2 Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Loss of Function of TGFBR1 in Cancer Generic Transcription Pathway Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: GMNN JUNB MEIS1 NPM1 PEX5	37 interactors: APLP2 ATF3 ATF4 BATF BATF2 BATF3 BCL6 BDNF BRCA1 C19orf68 DDIT3 EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG USP24 ZNF595
Entrez ID		3204	3726
HPRD ID		00838	01303
Ensembl ID		ENSG00000122592	ENSG00000171223
Uniprot IDs		P31268	P17275 Q5U079
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Endoribonuclease Activity Regulation Of EIF2 Alpha Phosphorylation By DsRNA Negative Regulation Of Protein Homotetramerization Regulation Of Cell Cycle Protein Import Into Peroxisome Matrix, Translocation Regulation Of Ribonuclease Activity Regulation Of Endodeoxyribonuclease Activity Developmental Process Protein Complex Assembly Protein Import Into Peroxisome Matrix, Docking Myeloid Cell Differentiation Organ Development Negative Regulation Of Protein Homooligomerization Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Osteoblast Proliferation Negative Regulation Of Protein Oligomerization Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Centriole Replication Embryonic Process Involved In Female Pregnancy Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Protein Import Into Peroxisome Matrix Blood Vessel Morphogenesis Protein Oligomerization Negative Regulation Of Centrosome Duplication Megakaryocyte Development Negative Regulation Of Cell Cycle System Development Blood Vessel Development Cellular Component Assembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Vasculature Development Megakaryocyte Differentiation Definitive Hemopoiesis Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Regulation Of RNA Metabolic Process Trophectodermal Cell Differentiation CENP-A Containing Nucleosome Assembly Labyrinthine Layer Blood Vessel Development Very Long-chain Fatty Acid Metabolic Process Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Negative Regulation Of Cellular Metabolic Process Lens Morphogenesis In Camera-type Eye	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Organic Substance Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Response To External Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Lipid Response To Mechanical Stimulus Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Response To Abiotic Stimulus Developmental Process Response To Corticosterone Response To Biotic Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Response To Mineralocorticoid Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		cdk2 cdk4 changes contribute conversely cyclin define diagnostic downregulation e1 endogenous forced hcc hepatocellular hepg2 knockdown morphogenesis observations organogenesis progression proliferation promising promoted qgy qsg roles sirna strategies	accumulated amplified clones delay differentiate differentiative ectopic epo erythroid erythropoietin evaluating g418 grow heavy introduced lg modifies modify neither plasmacytoma proliferated proliferative providing responsive retrovirally stat5 tepc transduced varied
Tagcloud (Difference) ?		cdk2 cdk4 changes contribute conversely cyclin define diagnostic downregulation e1 endogenous forced hcc hepatocellular hepg2 knockdown morphogenesis observations organogenesis progression proliferation promising promoted qgy qsg roles sirna strategies	accumulated amplified clones delay differentiate differentiative ectopic epo erythroid erythropoietin evaluating g418 grow heavy introduced lg modifies modify neither plasmacytoma proliferated proliferative providing responsive retrovirally stat5 tepc transduced varied
Tagcloud (Intersection) ?