HIST1H2AE and EID1

Number of citations of the paper that reports this interaction (PMID 11964378)
12

Data Source:
BioGRID (pull down)

		HIST1H2AE	EID1
Gene Name		histone cluster 1, H2ae	EP300 interacting inhibitor of differentiation 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Aggresome
	Molecular Function	DNA Binding Protein Heterodimerization Activity	Transcription Corepressor Activity Protein Binding Histone Acetyltransferase Regulator Activity Histone Acetyltransferase Binding
	Biological Process	Biological_process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cell Cycle Cell Differentiation Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression Packaging Of Telomere Ends Telomere Maintenance Nucleosome assembly RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance HDACs deacetylate histones Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Meiotic synapsis Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA Cell Cycle, Mitotic RMTs methylate histone arginines Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: EID1 NAP1L4	18 interactors: ARID4A CREBBP EP300 HIST1H2AE HIST1H2BB HIST1H3A HIST1H4A KAT2A MDM2 NCOA2 NDN NR0B2 PCID2 PSEN2 RB1 TRIM27 UBE3A XRCC6
Entrez ID		3012	23741
HPRD ID		04152	06907
Ensembl ID		ENSG00000168274	ENSG00000255302
Uniprot IDs		P04908 Q08AJ9	Q9Y6B2
PDB IDs		2CV5 3A6N 3AFA 3AN2 3AV1 3AV2 3AYW 3AZE 3AZF 3AZG 3AZH 3AZI 3AZJ 3AZK 3AZL 3AZM 3AZN 3W96 3W97 3W98 3W99
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromosome Organization Chromatin Organization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Peptidyl-lysine Modification Viral Process Positive Regulation Of Transcription, DNA-templated Chromatin Modification Histone Modification Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Acetylation Transcription, DNA-templated N-terminal Peptidyl-lysine Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation RNA Biosynthetic Process Protein Acetylation Organelle Organization Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Immune System Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression, Epigenetic DNA Replication-dependent Nucleosome Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Type I Interferon Production RNA Metabolic Process
Tagcloud ?			associates balance blastocyst block cbp collectively degraded developmental e3 embryonic esc escs hallmarks hat impede k48 lethality ligase maintenance mdm2 modulation pcid2 pluripotency renewal self suppression sustain switch ubiquitination
Tagcloud (Difference) ?			associates balance blastocyst block cbp collectively degraded developmental e3 embryonic esc escs hallmarks hat impede k48 lethality ligase maintenance mdm2 modulation pcid2 pluripotency renewal self suppression sustain switch ubiquitination
Tagcloud (Intersection) ?