EMC6 and MMD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMC6	MMD
Description		ER membrane protein complex subunit 6	monocyte to macrophage differentiation associated
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane EMC Complex Omegasome Membrane	Lysosome Lysosomal Membrane Endosome Golgi Apparatus Plasma Membrane Membrane Late Endosome Membrane
	Molecular Function	Protein Binding Membrane Insertase Activity	Protein Kinase Activity Protein Binding Signaling Receptor Activity Pore-forming Activity
	Biological Process	Autophagosome Assembly Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane	Regulation Of Protein Localization Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Kinase Activity
Pathways
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)
Interacting Genes		21 interacting genes: AQP6 AQP9 CD79A CREB3 EBP ELOVL4 ERGIC3 FAM209A FFAR2 MMD MUC1 PDZK1IP1 SLC10A1 SLC10A6 SLC35H1 SLC39A2 SLC71A2 SLC7A1 TLCD4 TMEM14B TMEM237	19 interacting genes: AGTRAP ARL13B ARLN ATP13A1 CYP4F2 EMC6 FAM209A GAST GPR152 GPX8 MS4A1 OCIAD1 PLEKHO1 SELENOK SFXN1 TMEM203 TMEM42 TMEM60 YIPF6
Entrez ID		83460	23531
HPRD ID		14529	06835
Ensembl ID		ENSG00000127774	ENSG00000108960
Uniprot IDs		Q9BV81	Q15546
PDB IDs		6WW7 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		Membrane Bile Acid:sodium Symporter Activity Transmembrane Transport Water Channel Activity Bile Acid And Bile Salt Transport Nitrate Transmembrane Transporter Activity One-carbon Compound Transport Fluid Transport Water Transport Channel Activity Organic Hydroxy Compound Transport Pyrimidine Nucleobase Transmembrane Transporter Activity Detoxification Of Arsenic-containing Substance Organic Anion Transport Positive Regulation Of Deacetylase Activity Cholesterol-5,6-oxide Hydrolase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane
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