GYPA and EVA1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GYPA	EVA1A
Description		glycophorin A (MNS blood group)	eva-1 homolog A, regulator of programmed cell death
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane Ankyrin-1 Complex	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Symbiont Entry Into Host Cell	Cardiac Left Ventricle Morphogenesis Energy Reserve Metabolic Process Autophagy Apoptotic Process Heart Development Post-embryonic Development Lung Development TOR Signaling Connective Tissue Replacement
Pathways		Cell surface interactions at the vascular wall	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder (body mass index interaction) ( 24322204) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease ( 25101718 30804561) Diabetic neuropathy in type 2 diabetes ( 33430853) Diastolic blood pressure ( 27841878) Femoral neck bone mineral density ( 30172743) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Lung function (low FEV1 vs high FEV1) ( 26423011) Major depressive disorder x sex interaction ( 34099189) Malaria ( 31844061) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Recurrent major depressive disorder x sex interaction ( 34099189) Red blood cell count ( 29403010) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Severe malaria ( 26416757) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White blood cell count ( 32888494)	Chronotype ( 30696823) Gout ( 32238385) Seborrheic dermatitis ( 29203360)
Interacting Genes		24 interacting genes: ANKRD29 CLDN5 CREB3 ELOVL4 ERGIC3 EVA1A FAM209A FFAR2 GOLT1A GPRC5D GPX8 KEAP1 LAPTM5 PDZK1IP1 SAR1A SGTA SGTB SLC10A6 TLCD4 TMBIM6 TMEM14B TMEM154 TMEM237 TMEM31	8 interacting genes: GYPA MAP1LC3B MS4A13 MTNR1B PTN SAT1 SGTB TSPAN4
Entrez ID		2993	84141
HPRD ID		07508	07827
Ensembl ID		ENSG00000170180	ENSG00000115363
Uniprot IDs		A0A2R8Y7F9 E9PD10 P02724 Q14419	Q9H8M9
PDB IDs		1AFO 2KPE 2KPF 5EH4 5EH6 7UZ3 7V07 7V0K 7V19 8CRQ 8CRR 8CRT 8CS9 8CSL 8CT3 8CTE
Enriched GO Terms of Interacting Partners?		Membrane TRC Complex Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Negative Regulation Of Response To Endoplasmic Reticulum Stress Golgi Vesicle Transport Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway COPII Vesicle Coating
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