GTF2A1 and HNRNPLL

		GTF2A1	HNRNPLL
Description		general transcription factor IIA subunit 1	heterogeneous nuclear ribonucleoprotein L like
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Cytoplasm Cytosol Transcription Preinitiation Complex	Nucleus Membrane Synapse Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	MRNA Processing Positive Regulation Of RNA Splicing Regulation Of RNA Splicing
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Neutrophil count ( 32888494) Night sleep phenotypes ( 27126917) Thyroid stimulating hormone levels ( 32769997) White blood cell count ( 32888494)	Body mass index ( 28892062)
Interacting Genes		26 interacting genes: BCL3 BIRC7 CREB1 CSNK2A1 CSNK2A2 GTF2A2 GTF2E1 GTF2E2 GTF2F1 HMGB1 NCOA6 NFYA PRR20A PRR20B PRR20C PRR20D PRR20E PSMC6 SP4 TAF1 TAF4 TAF4B TASP1 TBP TBPL1 TRIP4	57 interacting genes: ADAMTSL4 ATXN1 BANP BARD1 BCAS2 BHLHE40 BOLL CALCOCO2 CEBPA DAB1 DDX39A DDX39B DENND2D EFHC2 EIF4ENIF1 FAM9B GOPC HNRNPK HOOK1 IKZF3 KHDRBS2 KRT31 KRT40 KRTAP10-3 MAGED1 MDFI MID2 MREG PAXIP1 PCBP1 PCBP3 PNMA1 POLR1F PRPF6 PTBP1 QKI RBM10 RBM3 RBPMS REL RHOXF2 SKIL SNRPA SPRY2 SRSF11 SSX2IP SUMO2 TADA2A THAP1 TLE5 TMCC2 TRIM23 TRIM27 UBE2I USP10 VAC14 WEE2-AS1
Entrez ID		2957	92906
HPRD ID		02748	13667
Ensembl ID		ENSG00000165417	ENSG00000143889
Uniprot IDs		P52655	A0A0S2Z6K1 A8K894 Q8WVV9
PDB IDs		1NVP 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5M4S 6MZM 6O9L 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGI 7EGJ 7LBM 7NVR 7NVS 7NVT 7NVU 7NVY 7NVZ 7NW0 7ZWC 7ZWD 7ZX7 7ZX8 7ZXE 8BVW 8BYQ 8BZ1 8GXQ 8GXS 8S51 8S52 8S5N 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	7EVS
Enriched GO Terms of Interacting Partners?		RNA Polymerase II General Transcription Initiation Factor Activity DNA-templated Transcription Initiation Transcription Factor TFIID Complex Transcription Initiation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation DNA-templated Transcription Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Nucleobase-containing Compound Biosynthetic Process RNA Polymerase II General Transcription Initiation Factor Binding RNA Metabolic Process Nucleic Acid Metabolic Process Macromolecule Biosynthetic Process MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly RNA Polymerase II-specific DNA-binding Transcription Factor Binding MRNA Transcription Transcription Factor TFIIA Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Metabolic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Transcription Factor TFIIE Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II Protein Kinase CK2 Complex Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Protein-DNA Complex Assembly Nucleus Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Aryl Hydrocarbon Receptor Binding Male Germ Cell Nucleus Regulation Of Gene Expression	Nucleic Acid Binding Identical Protein Binding RNA Binding Regulation Of MRNA Processing MRNA Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Regulation Of MRNA Metabolic Process MRNA Processing RNA Splicing Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process PML Body MRNA Metabolic Process Nucleus Regulation Of RNA Splicing Regulation Of Transcription By RNA Polymerase II Nuclear Speck RNA Processing Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Splicing Nucleic Acid Metabolic Process Regulation Of Gene Expression Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Response To Cytokine Response To Peptide Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process SUMO Transferase Activity Regulation Of Metabolic Process Spliceosomal Complex Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process MRNA Stabilization Nuclear Export Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process
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