COMMD5 and COMMD1

Number of citations of the paper that reports this interaction (PMID 15799966)
52

Data Source:
HPRD (in vitro)

		COMMD5	COMMD1
Gene Name		COMM domain containing 5	copper metabolism (Murr1) domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Early Endosome Cul2-RING Ubiquitin Ligase Complex Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Copper Ion Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Identical Protein Binding Protein Homodimerization Activity Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process		Golgi To Plasma Membrane Transport Positive Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Plasma Membrane To Endosome Transport Copper Ion Homeostasis Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Protein Localization To Cell Surface
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: COMMD1	27 interactors: BAHCC1 BARD1 BRCA1 COMMD10 COMMD2 COMMD3 COMMD4 COMMD5 COMMD6 COMMD7 COMMD8 CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CUL7 KAT2A LIG4 NFKBIA RELA SLC12A2 SOCS1 SPP1 TCEB1 XIAP
Entrez ID		28991	150684
HPRD ID		16301	06253
Ensembl ID		ENSG00000170619
Uniprot IDs		Q9GZQ3	Q8N668
PDB IDs			2H2M
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Sodium Ion Transmembrane Transport Plasma Membrane To Endosome Transport Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Sodium Ion Transport Regulation Of Protein Localization To Cell Surface Copper Ion Homeostasis Golgi To Plasma Membrane Transport Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Sodium Ion Transport Post-Golgi Vesicle-mediated Transport Negative Regulation Of Ion Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Transition Metal Ion Homeostasis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Ubiquitination Endosomal Transport Golgi Vesicle Transport Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Catabolic Process Negative Regulation Of Transport Regulation Of Ion Transmembrane Transport Metal Ion Homeostasis Ion Homeostasis	Protein Ubiquitination Protein Modification By Small Protein Conjugation Viral Process Intrinsic Apoptotic Signaling Pathway Cell Cycle Arrest Ubiquitin-dependent Protein Catabolic Process Response To Stress Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Stress Apoptotic Signaling Pathway Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Cell Cycle Cellular Response To Stimulus Apoptotic Process Cell Cycle Negative Regulation Of Cell Cycle Programmed Cell Death Cell Death Death Response To Abiotic Stimulus Regulation Of Cell Proliferation G1/S Transition Of Mitotic Cell Cycle Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cellular Process Intracellular Signal Transduction Cell Cycle Process Response To Stimulus Proteolysis Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Modification Process Regulation Of Metabolic Process Protein Monoubiquitination Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cellular Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Phase Transition Protein K6-linked Ubiquitination Mitotic Cell Cycle Process Negative Regulation Of NF-kappaB Transcription Factor Activity Protein Metabolic Process Mitotic Cell Cycle Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Metabolic Process
Tagcloud ?		barrier burst exploration facilitating hcarg hypertension hypertensive immediately impairment injured kidneys mostly normotensive overexpressing p21 pathogenetic proximal re recover renal repair reperfusion requiring spontaneously transactivation transgenic tubular tubules unmet	beneficial cart comparative considering edged eradication hiv ikappab infected innate jak latency latent lymphoid murr1 parental poses proteasomal reactivation reinforcing respective restriction retroviral sets stabilized suppressing sword tnfalpha toll
Tagcloud (Difference) ?		barrier burst exploration facilitating hcarg hypertension hypertensive immediately impairment injured kidneys mostly normotensive overexpressing p21 pathogenetic proximal re recover renal repair reperfusion requiring spontaneously transactivation transgenic tubular tubules unmet	beneficial cart comparative considering edged eradication hiv ikappab infected innate jak latency latent lymphoid murr1 parental poses proteasomal reactivation reinforcing respective restriction retroviral sets stabilized suppressing sword tnfalpha toll
Tagcloud (Intersection) ?