LILRB3 and GRID1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LILRB3	GRID1
Description		leukocyte immunoglobulin like receptor B3	glutamate ionotropic receptor delta type subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Secretory Granule Membrane	Plasma Membrane Membrane AMPA Glutamate Receptor Complex Dendritic Spine Synapse Postsynaptic Membrane Extracellular Exosome Trans-synaptic Protein Complex Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Amyloid-beta Binding Transmembrane Signaling Receptor Activity Protein Binding Inhibitory MHC Class I Receptor Activity Signaling Receptor Activity	AMPA Glutamate Receptor Activity Monoatomic Ion Channel Activity Protein Binding Ligand-gated Monoatomic Ion Channel Activity GABA Receptor Activity Signaling Receptor Activity Identical Protein Binding G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Adaptive Immune Response Immune System Process Immune Response-regulating Signaling Pathway Defense Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Osteoclast Differentiation	Monoatomic Ion Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Synaptic Plasticity Monoatomic Ion Transmembrane Transport Social Behavior Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Synaptic Plasticity Modulation Of Chemical Synaptic Transmission Regulation Of Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Postsynapse Organization Synaptic Signaling Via Neuropeptide
Pathways
Drugs
Diseases
GWAS		Birth weight ( 31043758) Monocyte count ( 32888494) Takayasu arteritis ( 25604533)	Adult body size ( 32376654) Anorexia nervosa ( 23568457) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Balding ( 26926045) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body size at age 10 ( 32376654) Cardiac structure and function ( 19584346) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Femur bone mineral density x serum urate levels interaction ( 34046847) HDL cholesterol levels ( 32109663) Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Non-del(5q) myelodysplastic syndromes ( 31738830) Pancreatic cancer ( 23180869) Periodontal microbiota ( 22699663) Post-traumatic stress disorder symptoms in trauma-exposed soldiers ( 30999091) Renal overload gout ( 32238385) Smoking status (ever vs never smokers) ( 30643258) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Stearic acid (18:0) levels ( 23362303) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		3 interacting genes: CHRNA1 GRID1 RPL38	5 interacting genes: DLG2 EML1 GOPC LILRB3 MTDH
Entrez ID		11025	2894
HPRD ID		11995	17078
Ensembl ID		ENSG00000204577	ENSG00000182771
Uniprot IDs		C9JWL8	A8KAN9 Q9ULK0
PDB IDs			8BLJ 8BN2 8BN5
Enriched GO Terms of Interacting Partners?		Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Synapse Regulation Of Postsynaptic Membrane Potential 90S Preribosome Assembly Eukaryotic 80S Initiation Complex Monoatomic Ion Channel Activity Postsynaptic Membrane G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential Negative Regulation Of Synaptic Plasticity Skeletal Muscle Tissue Growth Chemical Synaptic Transmission GABA Receptor Activity Trans-synaptic Protein Complex AMPA Glutamate Receptor Activity Axial Mesoderm Development Trans-synaptic Signaling Synaptic Signaling Acetylcholine Binding Synaptic Signaling Via Neuropeptide Regulation Of Membrane Potential Acetylcholine Receptor Activity Musculoskeletal Movement Acetylcholine-gated Monoatomic Cation-selective Channel Activity Modulation Of Chemical Synaptic Transmission Acetylcholine-gated Channel Complex Cell-cell Signaling Middle Ear Morphogenesis Synaptic Transmission, Cholinergic Signaling Muscle Cell Cellular Homeostasis Cell Communication AMPA Glutamate Receptor Complex Neuronal Action Potential Monoatomic Ion Transmembrane Transport Neuromuscular Synaptic Transmission Postsynaptic Specialization Membrane Ionotropic Glutamate Receptor Signaling Pathway Ligand-gated Monoatomic Ion Channel Activity Skeletal Muscle Contraction Extracellular Ligand-gated Monoatomic Ion Channel Activity Neuromuscular Junction Development Presynaptic Modulation Of Chemical Synaptic Transmission Response To Nicotine Acetylcholine Receptor Signaling Pathway Nervous System Process Synaptic Transmission, Glutamatergic Ligand-gated Ion Channel Signaling Pathway Monoatomic Ion Transport Postsynaptic Signal Transduction Glutamate Receptor Signaling Pathway	Retrograde Axonal Protein Transport Negative Regulation Of Anion Channel Activity
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