SCAI and CDIPT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SCAI	CDIPT
Description		suppressor of cancer cell invasion	CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Transcription Corepressor Activity Protein Binding	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Protein Binding Transferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Diacylglycerol Binding Manganese Ion Binding Carbohydrate Binding Alcohol Binding Metal Ion Binding
	Biological Process	DNA-templated Transcription Negative Regulation Of Signal Transduction Negative Regulation Of Cell Migration Negative Regulation Of Rho Protein Signal Transduction Negative Regulation Of DNA-templated Transcription	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Metabolic Process
Pathways		RHO GTPases Activate Formins	Synthesis of PI
Drugs			scyllo-inositol
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Pulse pressure ( 28135244 30578418) Refractive error ( 32231278) Smoking cessation ( 33082346) Worry too long after an embarrassing experience ( 29500382)	Mean platelet volume ( 27863252)
Interacting Genes		6 interacting genes: CDIPT ITPKB ITSN1 OGT PIN1 SOX7	60 interacting genes: APP AQP2 AQP6 ARL13B ATP6V0E1 BSND CD79A CGRRF1 CISD2 CPLX4 CYB561 CYB5R3 DARS2 EBP ELOVL4 ERGIC3 EVI2B FAM209A FCER1G FCGR2A FFAR2 FKBP7 GJB1 GOLM1 GPR101 GPR151 GPR152 GPX8 HSD17B13 IER3IP1 IGFBP6 JAGN1 KCNK1 KIR2DL3 LNX1 MFF MGST3 MS4A14 MTIF3 ODF4 PLP1 PSCA RELL2 RETREG3 RNF19B RPLP1 RTN3 SCAI SCN3B SDCBP SIGLEC12 SLC10A1 SLC10A6 SLC16A7 SLC7A1 SSMEM1 TLCD4 TMX2 UNC93A VMA21
Entrez ID		286205	10423
HPRD ID		12941	12063
Ensembl ID		ENSG00000173611	ENSG00000103502
Uniprot IDs		Q8N9R8	A8K3L7 O14735
PDB IDs
Enriched GO Terms of Interacting Partners?		Glycerophospholipid Biosynthetic Process Phosphatidylinositol Metabolic Process Positive Regulation Of Cell Communication Regulation Of Neutrophil Apoptotic Process Phospholipid Biosynthetic Process Regulation Of Small GTPase Mediated Signal Transduction Common Myeloid Progenitor Cell Proliferation Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Positive Regulation Of Signaling Phosphatidylinositol Biosynthetic Process Inositol Trisphosphate Metabolic Process Inositol-1,4,5-trisphosphate 3-kinase Activity Negative Regulation Of Neutrophil Apoptotic Process Phosphoserine Residue Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Peptidyl-prolyl Isomerization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Phosphothreonine Residue Binding Glutamatergic Synapse Cis-trans Isomerase Activity Negative Regulation Of Protein Catabolic Process Positive Regulation Of Caveolin-mediated Endocytosis Clathrin-dependent Synaptic Vesicle Endocytosis Regulation Of Caveolin-mediated Endocytosis Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein N-acetylglucosaminyltransferase Complex Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Alcohol Binding Inositol Hexakisphosphate Kinase Activity Glycerophospholipid Metabolic Process Postsynaptic Endocytic Zone Positive Regulation Of Growth Hormone Secretion Regulation Of Transcription By Glucose Mitogen-activated Protein Kinase Kinase Binding Postsynaptic Actin Cytoskeleton Positive Thymic T Cell Selection Inositol Phosphate Biosynthetic Process GTPase Activating Protein Binding Ubiquitin Ligase Activator Activity Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway NSL Complex	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Organization Plasma Membrane Identical Protein Binding Bile Acid:sodium Symporter Activity
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