SYPL2 and YIPF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYPL2	YIPF2
Description		synaptophysin like 2	Yip1 domain family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Membrane Synaptic Vesicle Membrane	Golgi Trans Cisterna Endosome Golgi Apparatus Golgi Medial Cisterna Trans-Golgi Network Endomembrane System Membrane Transport Vesicle Late Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding Small GTPase Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Heart Development Substantia Nigra Development T-tubule Organization	Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Body mass index ( 29273807) Chronic kidney disease ( 20383146) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Estimated glomerular filtration rate ( 31015462 31152163) Glomerular filtration rate (creatinine) ( 26831199 28452372) Major depressive disorder ( 20125088)
Interacting Genes		7 interacting genes: ATP13A1 GET3 PLLP SLC38A7 SLC41A1 SNCA YIPF2	24 interacting genes: AQP6 CREB3 ERGIC3 FATE1 FFAR2 GPR42 HSD17B13 LEPROTL1 PGRMC2 RNF185 RNF5 SHISAL2A SLC10A6 SLC30A2 SLC39A3 SLC71A2 SPCS1 STING1 SYPL2 TMEM143 TMEM14B TMX2 TVP23B YIPF6
Entrez ID		284612	78992
HPRD ID		17478	11332
Ensembl ID		ENSG00000143028	ENSG00000130733
Uniprot IDs		B4DYR7 Q5VXT5	K7ENM8 Q9BWQ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Magnesium Ion Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Monoatomic Ion Transport L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Inorganic Ion Homeostasis Monoatomic Ion Homeostasis Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Monoatomic Cation Homeostasis Regulation Of Transcytosis Magnesium:sodium Antiporter Activity GET Complex Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Asparagine Transport L-asparagine Transmembrane Transporter Activity P-type Transmembrane Transporter Activity Metal Ion Transport Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Compact Myelin P-type Ion Transporter Activity Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Cellular Response To Metal Ion Dopamine Uptake Involved In Synaptic Transmission Sodium Ion Transport Intracellular Magnesium Ion Homeostasis Cellular Response To Magnesium Ion Monoatomic Cation Transport Establishment Of Protein Localization To Membrane Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Calcium Ion Homeostasis Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Glutamine Transport L-glutamine Transmembrane Transporter Activity Golgi Trans Cisterna Inorganic Cation Transmembrane Transporter Activity	Membrane Endoplasmic Reticulum Ubiquitin-like Protein Conjugating Enzyme Binding Endoplasmic Reticulum Membrane Transmembrane Transport Endoplasmic Reticulum Mannose Trimming Protein Alpha-1,2-demannosylation Positive Regulation Of Type I Interferon-mediated Signaling Pathway Identical Protein Binding Protein Deglycosylation Zinc Ion Transmembrane Transporter Activity Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Endoplasmic Reticulum Quality Control Compartment Zinc Ion Transmembrane Transport Zinc Ion Transport CGAS/STING Signaling Pathway Nitrate Transmembrane Transporter Activity Monoatomic Ion Transport Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Positive Regulation Of Deacetylase Activity COPII-coated ER To Golgi Transport Vesicle Cyclic-di-GMP Binding STING Complex Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Pattern Recognition Receptor Signaling Pathway Golgi Membrane Regulation Of Type I Interferon-mediated Signaling Pathway Innate Immune Response-activating Signaling Pathway Mitochondrial Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Retrograde Transporter Complex, Golgi To ER 2',3'-cyclic GMP-AMP Binding Activation Of Innate Immune Response Mitochondrial Outer Membrane Protein Binding Monoatomic Cation Transport Positive Regulation Of Cytokine-mediated Signaling Pathway
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