MAMSTR and MYOCD

Number of citations of the paper that reports this interaction (PMID 16818234)
29

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		MAMSTR	MYOCD
Gene Name		MEF2 activating motif and SAP domain containing transcriptional regulator	myocardin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Transcription Factor Binding Transcription Factor Activity	Core Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Coactivator Activity Protein Binding Transcription Factor Binding Histone Acetyltransferase Binding Histone Deacetylase Binding R-SMAD Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Positive Regulation Of Myotube Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Growth By Extracellular Stimulus Vasculogenesis Response To Hypoxia Cardiac Ventricle Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Myotube Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cardiocyte Differentiation Regulation Of Histone Acetylation Hepatic Stellate Cell Activation Positive Regulation Of DNA Binding Cellular Component Maintenance Regulation Of Myoblast Differentiation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Smooth Muscle Contraction Lung Alveolus Development Digestive Tract Development Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Smooth Muscle Cell Differentiation Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of Smooth Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Ventricular Cardiac Muscle Cell Differentiation Uterus Development Urinary Bladder Development Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Growth Factor Stimulus Cellular Response To Hypoxia Ductus Arteriosus Closure Negative Regulation Of Beta-amyloid Clearance Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Differentiation Negative Regulation Of Skeletal Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Multiple sclerosis ( 21833088) Pubertal anthropometrics ( 23449627)	Testosterone levels ( 22675492)
Protein-Protein Interactions		1 interactors: MYOCD	12 interactors: GOPC GSK3B KDM3A MAMSTR MKL1 MYOD1 SMAD2 SMAD3 SMARCA4 SRF STUB1 UBC
Entrez ID		284358	93649
HPRD ID		08204	09362
Ensembl ID		ENSG00000176909	ENSG00000141052
Uniprot IDs		Q6ZN01	Q6N065 Q8IZQ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Hepatic Stellate Cell Activation Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation Negative Regulation Of Beta-amyloid Clearance Negative Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Cell Growth By Extracellular Stimulus Fibroblast Activation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation Positive Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Urinary Bladder Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Ductus Arteriosus Closure Regulation Of Beta-amyloid Clearance Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Negative Regulation Of Myotube Differentiation Cardiac Muscle Cell Myoblast Differentiation Negative Regulation Of Striated Muscle Cell Apoptotic Process Cardioblast Differentiation Uterus Development Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Differentiation Regulation Of Skeletal Muscle Cell Differentiation Negative Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cardiac Muscle Hypertrophy Cellular Component Maintenance Positive Regulation Of Smooth Muscle Contraction Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Muscle Hypertrophy Ventricular Cardiac Muscle Cell Differentiation Cardiac Muscle Tissue Growth Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of DNA Binding Regulation Of Myoblast Differentiation Negative Regulation Of Muscle Cell Differentiation Myoblast Differentiation Negative Regulation Of Striated Muscle Tissue Development Regulation Of Histone Acetylation Negative Regulation Of Muscle Organ Development Lung Alveolus Development Regulation Of Smooth Muscle Contraction Regulation Of Muscle Cell Apoptotic Process Smooth Muscle Cell Differentiation Artery Morphogenesis Regulation Of Myotube Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Cardiac Muscle Tissue Development	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Signaling Regulation Of Cellular Component Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Regulation Of Binding Transcription, DNA-templated Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Developmental Growth RNA Biosynthetic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Signal Transduction Muscle Cell Differentiation Cellular Nitrogen Compound Metabolic Process Cell Development Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Response To Transforming Growth Factor Beta Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Stem Cell Differentiation Regulation Of RNA Biosynthetic Process RNA Metabolic Process Growth Regulation Of RNA Metabolic Process Smooth Muscle Cell Differentiation Positive Regulation Of Cell Development Regulation Of Gene Expression, Epigenetic Muscle Structure Development Primary MiRNA Processing Regulation Of Cell Differentiation
Tagcloud ?			adaptation associate cardiac cardioenriched circuits close coactivators cofactors correlate directing discovered discuss entertained focus growing identifies inputs modulation mrtf networks nevertheless overlapping participate precise preclinical putative regulatory understand
Tagcloud (Difference) ?			adaptation associate cardiac cardioenriched circuits close coactivators cofactors correlate directing discovered discuss entertained focus growing identifies inputs modulation mrtf networks nevertheless overlapping participate precise preclinical putative regulatory understand
Tagcloud (Intersection) ?