GATC and SRSF11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		GATC	SRSF11
Description		glutamyl-tRNA amidotransferase subunit C	serine and arginine rich splicing factor 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Glutamyl-tRNA(Gln) Amidotransferase Complex	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Ligase Activity Carbon-nitrogen Ligase Activity, With Glutamine As Amido-N-donor Glutaminyl-tRNA Synthase (glutamine-hydrolyzing) Activity	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Translation Regulation Of Translational Fidelity Mitochondrial Translation Glutaminyl-tRNAGln Biosynthesis Via Transamidation	MRNA Processing RNA Splicing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397) Reticulocyte count ( 32888494)
Interacting Genes		6 interacting genes: ALOX5 CTAG1A CTAG1B HGS SRSF11 TOMM20L	33 interacting genes: ARL6IP4 ATP5F1D CDK6 CSNK2A1 DACH1 DDOST DUSP29 ETS1 GATC HNRNPLL HYI LNX2 MDM2 MEOX2 OGT PAK5 PAX6 PIN1 PUF60 RAB2B RNPS1 SDCBP SREK1 SRPK2 SRRM4 SRSF1 SRSF2 TANK THAP11 TOP1 U2AF2 ZC3HAV1 ZNF385C
Entrez ID		283459	9295
HPRD ID		15934	03599
Ensembl ID		ENSG00000257218	ENSG00000116754
Uniprot IDs		O43716	Q05519 Q5T757 Q5T760
PDB IDs
Enriched GO Terms of Interacting Partners?		TRNA Threonylcarbamoyladenosine Metabolic Process Leukotriene A4 Metabolic Process Arachidonate Metabolite Production Involved In Inflammatory Response Leukotriene Production Involved In Inflammatory Response Leukotriene A4 Biosynthetic Process Arachidonate 5-lipoxygenase Activity Negative Regulation Of Vasculature Development Arachidonate 8(S)-lipoxygenase Activity Lipoxin Biosynthetic Process Arachidonate 12(S)-lipoxygenase Activity Negative Regulation Of Angiogenesis Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen ESCRT-0 Complex Phagocytic Vesicle Lumen TRNA Import Into Mitochondrion Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Epoxide Metabolic Process RNA Import Into Mitochondrion Mitochondrion Targeting Sequence Binding TRNA Transport TRNA Metabolic Process Negative Regulation Of Vascular Wound Healing Protein Targeting Leukocyte Chemotaxis Involved In Inflammatory Response Mitochondrial Outer Membrane Translocase Complex Lipoxygenase Pathway	Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Nuclear Speck Regulation Of MRNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Splicing Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Nucleic Acid Binding Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nucleic Acid Metabolic Process RNA Binding Nucleus Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Splicing Regulation Of Cell Motility Regulation Of Locomotion Protein Binding Nuclear Body Organization Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome Chromatin DNA Binding Negative Regulation Of Macromolecule Metabolic Process Exon-exon Junction Complex RNA Splicing, Via Transesterification Reactions Positive Regulation Of Type I Interferon Production Sin3-type Complex Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Cell Cycle Protein Serine/threonine Kinase Activity Negative Regulation Of MRNA Metabolic Process Alternative MRNA Splicing, Via Spliceosome
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