GATC

Description		glutamyl-tRNA amidotransferase subunit C
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Glutamyl-tRNA(Gln) Amidotransferase Complex
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Ligase Activity Carbon-nitrogen Ligase Activity, With Glutamine As Amido-N-donor Glutaminyl-tRNA Synthase (glutamine-hydrolyzing) Activity
	Biological Process	Translation Regulation Of Translational Fidelity Mitochondrial Translation Glutaminyl-tRNAGln Biosynthesis Via Transamidation
Pathways
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397) Reticulocyte count ( 32888494)
Novel Interacting Genes		1 novel interacting genes: DNAH10
Interacting Genes		6 interacting genes: ALOX5 CTAG1A CTAG1B HGS SRSF11 TOMM20L
Entrez ID		283459
HPRD ID		15934
Ensembl ID		ENSG00000257218
Uniprot IDs		O43716
PDB IDs
Enriched GO Terms of Interacting Partners?		TRNA Threonylcarbamoyladenosine Metabolic Process Leukotriene A4 Metabolic Process Arachidonate Metabolite Production Involved In Inflammatory Response Leukotriene Production Involved In Inflammatory Response Leukotriene A4 Biosynthetic Process Arachidonate 5-lipoxygenase Activity Negative Regulation Of Vasculature Development Arachidonate 8(S)-lipoxygenase Activity Lipoxin Biosynthetic Process Arachidonate 12(S)-lipoxygenase Activity Negative Regulation Of Angiogenesis Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen ESCRT-0 Complex Phagocytic Vesicle Lumen TRNA Import Into Mitochondrion Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Epoxide Metabolic Process RNA Import Into Mitochondrion Mitochondrion Targeting Sequence Binding TRNA Transport TRNA Metabolic Process Negative Regulation Of Vascular Wound Healing Protein Targeting Leukocyte Chemotaxis Involved In Inflammatory Response Mitochondrial Outer Membrane Translocase Complex Lipoxygenase Pathway
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