MORN3 and HOXB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MORN3	HOXB2
Description		MORN repeat containing 3	homeobox B2
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasmic Vesicle	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Signal Transduction By P53 Class Mediator Negative Regulation Of Signal Transduction By P53 Class Mediator	Morphogenesis Of An Epithelial Sheet Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Rhombomere 3 Development Rhombomere 4 Development Facial Nerve Structural Organization Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Skeletal System Morphogenesis Neural Nucleus Development
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS			Body mass index ( 26426971) Experiencing mood swings ( 29500382) Feeling hurt ( 29500382) Keratoconus ( 33649486) Primary tooth development (number of teeth) ( 20195514)
Interacting Genes		66 interacting genes: ABHD11 ADAMTSL4 ARID5A BEX2 C14orf119 CDCA7L CFTR CIMIP2B CTDSP1 DYNLL1 DYNLL2 EIF3D ENKD1 FAM90A1 FANCL FARS2 FTO GEM GLYCTK GOLGA2 GPANK1 GUCD1 HOOK2 HOXB2 IKZF3 INO80B KANK2 KLHL38 KRT15 LHX2 LZTS2 MAGEA6 MB21D2 MEOX2 MISP MKRN3 MLH1 MYOZ3 NDUFAB1 NFU1 NOXA1 NTAQ1 OIP5 PAX6 PHF1 PICK1 POLR1C PRKAA2 PRKAB2 PRR5L RBPMS RNF39 RSPH1 RUSC1 SCNM1 SH2D4A SOX5 SUOX TASOR2 TEKT4 TRAF1 TRAF2 TRIP13 YPEL3 ZNF438 ZNF76	13 interacting genes: CREBBP DTX2 EP300 MID2 MNDA MORN3 NDOR1 PBX4 RCHY1 RUNX1T1 SOD1 UBASH3B ZNF410
Entrez ID		283385	3212
HPRD ID		17330	00854
Ensembl ID		ENSG00000139714	ENSG00000173917
Uniprot IDs		Q6PF18	P14652
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Protein Binding	Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Zinc Ion Binding P53 Binding N-terminal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Nucleus Regulation Of Cellular Response To Heat Acetyltransferase Activity Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Transcription Coregulator Activity Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Activity Protein Acetylation DNA-binding Transcription Factor Binding Phosphoprotein Binding Activation Of Innate Immune Response Tau Protein Binding Transcription Coactivator Binding Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity Protein Destabilization Canonical NF-kappaB Signal Transduction Damaged DNA Binding Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Activation Transcription Coactivator Activity Positive Regulation Of Innate Immune Response Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Peptide Crotonyltransferase Activity Response To Antipsychotic Drug Action Potential Initiation
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