ABO and GRAMD3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ABO	GRAMD3
Gene Name		ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	GRAM domain containing 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Integral Component Of Membrane Golgi Cisterna Membrane	Cytoplasmic Microtubule
	Molecular Function	Glycoprotein-fucosylgalactoside Alpha-N-acetylgalactosaminyltransferase Activity Fucosylgalactoside 3-alpha-galactosyltransferase Activity Metal Ion Binding
	Biological Process	Protein Glycosylation
Pathways
Drugs		Uridine-Diphosphate-N-Acetylgalactosamine Uridine-5\'-Diphosphate Uridine Diphosphate Galactose 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,5-Diol 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol H TYPE II TRISACCHARIDE H TYPE I TRISACCHARIDE GALACTOSE GREASE BETA-METHYLLACTOSIDE octyl 3-amino-3-deoxy-2-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-galactopyranoside 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL 4-AMINO-2-OCTYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Angiotensin-converting enzyme activity ( 20066004) Cholesterol, total ( 20686565) Coagulation factor levels ( 23267103) Coronary heart disease ( 21239051 21378990) D-dimer levels ( 21502573) Duodenal ulcer ( 22387998) E-selectin levels ( 20147318) End-stage coagulation ( 23381943) Graves' disease ( 21841780 23612905) Hematological and biochemical traits ( 20139978) Inflammatory biomarkers ( 22291609) LDL cholesterol ( 20686565) Liver enzyme levels ( 18940312) Liver enzyme levels (alkaline phosphatase) ( 22001757) Malaria ( 22895189 23717212) mean corpuscular hemoglobin concentration ( 20139978) Metabolic traits ( 21886157) Metabolite levels ( 21909109) Obesity-related traits ( 23251661) Pancreatic cancer ( 19648918) Phytosterol levels ( 20529992) Protein biomarker ( 23056639) Protein quantitative trait loci ( 18464913) Red blood cell count ( 20139978) Red blood cell traits ( 23222517) Soluble E-selectin levels ( 19729612) Soluble ICAM-1 ( 21533024 18604267) Soluble levels of adhesion molecules ( 20167578) Thyroid hormone levels ( 23408906) Tumor biomarkers ( 23300138) Venous thromboembolism ( 21980494 23650146 19278955 22672568)	Cognitive performance ( 20125193) Diabetic retinopathy ( 21441570)
Protein-Protein Interactions		2 interactors: GRAMD3 TMEM79	6 interactors: ABO FRMD8 GIMAP5 MORF4L2 NAPRT PAEP
Entrez ID		28	65983
HPRD ID		05821	11402
Ensembl ID			ENSG00000155324
Uniprot IDs		P16442	Q96HH9
PDB IDs		1LZ0 1LZ7 1LZI 1LZJ 1R7T 1R7U 1R7V 1R7X 1R7Y 1R80 1R81 1R82 1WSZ 1WT0 1WT1 1WT2 1WT3 1XZ6 1ZHJ 1ZI1 1ZI3 1ZI4 1ZI5 1ZIZ 1ZJ0 1ZJ1 1ZJ2 1ZJ3 1ZJO 1ZJP 2A8U 2A8W 2I7B 2O1F 2O1G 2O1H 2PGV 2PGY 2RIT 2RIX 2RIY 2RIZ 2RJ0 2RJ1 2RJ4 2RJ5 2RJ6 2RJ7 2RJ8 2RJ9 2Y7A 3I0C 3I0D 3I0E 3I0F 3I0G 3I0H 3I0I 3I0J 3I0K 3I0L 3IOH 3IOI 3IOJ 3SX3 3SX5 3SX7 3SX8 3SXA 3SXB 3SXC 3SXD 3SXE 3SXG 3U0X 3U0Y 3V0L 3V0M 3V0N 3V0O 3V0P 3V0Q 3ZGF 4C2S 4KC1 4KC2 4KC4
Enriched GO Terms of Interacting Partners?		Cuticle Development Cornification Establishment Of Skin Barrier Regulation Of Water Loss Via Skin Epithelial Cell Maturation Positive Regulation Of Epidermis Development Hair Follicle Morphogenesis Epidermis Morphogenesis Keratinization Multicellular Organismal Water Homeostasis Skin Morphogenesis Regulated Secretory Pathway Water Homeostasis Regulation Of Epidermis Development Keratinocyte Differentiation Hair Follicle Development Hair Cycle Process Hair Cycle Epidermal Cell Differentiation Cell Maturation Epithelial Cell Development Skin Development Epidermis Development Exocytosis Secretion By Cell Morphogenesis Of An Epithelium Epithelial Cell Differentiation Regulation Of Body Fluid Levels	Nicotinate Nucleotide Salvage Nicotinamide Metabolic Process Alkaloid Metabolic Process
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