ADAMDEC1 and GPAA1

		ADAMDEC1	GPAA1
Description		ADAM like decysin 1	glycosylphosphatidylinositol anchor attachment 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex
	Molecular Function	Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding	GPI-anchor Transamidase Activity Protein Binding GPI Anchor Binding
	Biological Process	Proteolysis Immune Response Negative Regulation Of Cell Adhesion	GPI Anchor Biosynthetic Process Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis
Pathways			Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Hair greying ( 26926045)	Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944)
Interacting Genes			10 interacting genes: AGTR1 AQP2 EIF3E GNRHR GRIK5 PIGK PIGT PIGU PIN1 PRR13
Entrez ID		27299	8733
HPRD ID		07070	04334
Ensembl ID		ENSG00000134028	ENSG00000197858
Uniprot IDs		B7Z6V5 O15204	O43292
PDB IDs			7W72 7WLD 8IMX 8IMY
Enriched GO Terms of Interacting Partners?		GPI-anchor Transamidase Activity GPI-anchor Transamidase Complex Protein Maturation Attachment Of GPI Anchor To Protein GPI Anchor Binding GPI Anchored Protein Biosynthesis Protein Retention In ER Lumen Tetraspanin-enriched Microdomain Maintenance Of Protein Localization In Endoplasmic Reticulum GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Regulation Of Membrane Protein Ectodomain Proteolysis Maintenance Of Protein Localization In Organelle Negative Regulation Of Notch Signaling Pathway Maintenance Of Protein Location In Cell Maintenance Of Protein Location Glycolipid Biosynthetic Process Maintenance Of Location In Cell Maintenance Of Location Glycolipid Metabolic Process Regulation Of Notch Signaling Pathway Phosphatidylinositol Biosynthetic Process	GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Attachment Of GPI Anchor To Protein GPI Anchor Binding GPI-anchor Transamidase Activity GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Glycerolipid Metabolic Process Phosphatidylinositol Metabolic Process Gamma-tubulin Binding Glycerophospholipid Biosynthetic Process Angiotensin Type I Receptor Activity Cis-trans Isomerase Activity Negative Regulation Of ARF Protein Signal Transduction Membrane Lipid Metabolic Process
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