ZNF688 and GMPPA

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		ZNF688	GMPPA
Description		zinc finger protein 688	GDP-mannose pyrophosphorylase A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Extracellular Exosome GDP-mannose Pyrophosphorylase Complex
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Mannose-1-phosphate Guanylyltransferase (GTP) Activity Enzyme Inhibitor Activity Protein Binding Transferase Activity Enzyme Binding Molecular Sensor Activity
	Biological Process	Regulation Of DNA-templated Transcription	Protein Glycosylation Glycoprotein Metabolic Process GDP-mannose Biosynthetic Process Negative Regulation Of Biosynthetic Process GDP-mannose Metabolic Process Telencephalon Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Phosphate Metabolic Process Muscle Organ Morphogenesis Cognition Neuromuscular Process Neuron Apoptotic Process Skeletal Muscle Organ Development Motor Behavior Negative Regulation Of Small Molecule Metabolic Process
Pathways		Generic Transcription Pathway	Synthesis of GDP-mannose
Drugs
Diseases
GWAS
Interacting Genes		111 interacting genes: ABI2 AIRIM ANKRD11 BEND5 BLZF1 BOLA2 BOLA2B CADPS CALCOCO2 CARD9 CATSPER1 CBY2 CCDC102B CCDC136 CCDC33 CCDC57 CCNC CDKN2D CDR2L CEP44 CEP70 CEP72 CIB3 CRX DEF6 EHMT2 FAM90A1 FBXO7 FCHO1 FHL5 GEM GLYCTK GMPPA GOLGA2 GPANK1 GPRASP2 HMBOX1 HNRNPK HOMEZ HOXA1 HSF2BP IGFN1 IHO1 KHDRBS2 KHDRBS3 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-9 KRTAP12-2 KRTAP4-2 LDOC1 LMO1 LMO2 MAGED1 MDFI MEOX2 MID2 MIPOL1 MKRN3 MYOZ3 NCK2 NEK6 NFU1 NOTCH2NLA OSTF1 PCBD1 PFKFB1 PHF1 PIH1D2 PLSCR1 PNMA1 PNMA2 POLR1C PSMA3 PSMB1 PSTPIP1 RCOR3 REL RFX6 RINT1 RPGRIP1 SCNM1 SMARCB1 SPAG5 SSX2IP TADA2A TCEANC TCF12 TCF4 TCP11 TEKT4 TENT5B TLE5 TMCC2 TNS2 TRAF1 TRAF2 TRAF4 TRIM23 TRIM27 TRIP6 TTC19 USHBP1 WWP2 ZC4H2 ZGPAT ZNF330	10 interacting genes: AKT1 BTC CDR2 CRP DCUN1D1 GMPPB GPKOW LSM8 NCK1 ZNF688
Entrez ID		146542	29926
HPRD ID		14070	13588
Ensembl ID		ENSG00000229809	ENSG00000144591
Uniprot IDs		A0A0S2Z5X4 A0A0S2Z633 P0C7X2	A0A384MDS7 Q96IJ6
PDB IDs			7D72 7D73 7D74
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Keratin Filament Nucleus Intermediate Filament Signaling Adaptor Activity Cytoskeleton Thioesterase Binding Transcription Coactivator Activity Microtubule Organizing Center Organization	Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
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