KCNH5 and KCNH1

Number of citations of the paper that reports this interaction (PMID 11943152)
11

Data Source:
HPRD (in vitro)

		KCNH5	KCNH1
Gene Name		potassium channel, voltage gated eag related subfamily H, member 5	potassium channel, voltage gated eag related subfamily H, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface	Nuclear Inner Membrane Nucleoplasm Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Phosphorelay Sensor Kinase Activity Voltage-gated Potassium Channel Activity Calmodulin Binding	Phosphorelay Sensor Kinase Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Phosphorelay Signal Transduction System Synaptic Transmission Regulation Of G2/M Transition Of Mitotic Cell Cycle Signal Transduction By Phosphorylation Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Potassium Ion Transmembrane Transport	Phosphorelay Signal Transduction System Potassium Ion Transport Synaptic Transmission Myoblast Fusion Signal Transduction By Phosphorylation Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Potassium Ion Transmembrane Transport
Pathways		Potassium Channels Voltage gated Potassium channels	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS		Major depressive disorder ( 23377640) Subcutaneous adipose tissue ( 22589738)	Circulating vasoactive peptide levels ( 23381795)
Protein-Protein Interactions		1 interactors: KCNH1	9 interactors: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 SDCBP WDYHV1
Entrez ID		27133	3756
HPRD ID		10421	04492
Ensembl ID		ENSG00000140015
Uniprot IDs		Q8NCM2	O95259
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-histidine Phosphorylation Phosphorelay Signal Transduction System Myoblast Fusion Syncytium Formation Myotube Differentiation	Synaptic Transmission Regulation Of Ion Transmembrane Transport Cell-cell Signaling Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Ion Transport Monovalent Inorganic Cation Transport Protein Homooligomerization Energy Derivation By Oxidation Of Organic Compounds Metal Ion Transport Cation Transmembrane Transport Generation Of Precursor Metabolites And Energy Protein Oligomerization Cation Transport Ion Transmembrane Transport Energy Reserve Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Transmembrane Transport Ion Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Component Assembly Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Peptidyl-histidine Phosphorylation Transport Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Detection Of Calcium Ion Substrate-dependent Cell Migration, Cell Extension Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Protein Complex Assembly Regulation Of Cellular Localization Phosphorelay Signal Transduction System Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Signaling Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Cell Communication Polysaccharide Catabolic Process
Tagcloud ?			1c currents eag eag1 elk erg erg1 governed heag1 herg imbalance immuno itim kcnh2 kv10 kv11 kv12 nothing phosphatases pp1 prototypes ptp ptpn6 qt shp src40 subfamilies superfamily underlie
Tagcloud (Difference) ?			1c currents eag eag1 elk erg erg1 governed heag1 herg imbalance immuno itim kcnh2 kv10 kv11 kv12 nothing phosphatases pp1 prototypes ptp ptpn6 qt shp src40 subfamilies superfamily underlie
Tagcloud (Intersection) ?