GIPR

Gene Name		gastric inhibitory polypeptide receptor
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Gastric Inhibitory Peptide Receptor Activity Peptide Hormone Binding
	Biological Process	Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Generation Of Precursor Metabolites And Energy Cell Surface Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Response To Glucose Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Gastric Inhibitory Peptide Signaling Pathway Response To Axon Injury Response To Calcium Ion Response To Fatty Acid
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Glucagon-type ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Body mass index ( 22344219 22344221 20935630) Obesity ( 23563607) Subcutaneous adipose tissue ( 22589738) Two-hour glucose challenge ( 20081857)
Protein-protein Interactions		2 interactors: GIP LNX1
Entrez ID		2696
HPRD ID		00670
Ensembl ID		ENSG00000010310
Uniprot IDs		B7WP14 P48546
PDB IDs		2QKH 4HJ0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glucagon Secretion Response To Selenium Ion Regulation Of Glucagon Secretion Positive Regulation Of CAMP-mediated Signaling Regulation Of CAMP-mediated Signaling Exploration Behavior Triglyceride Homeostasis Acylglycerol Homeostasis
Tagcloud ?		3t3 adipocyte adipocytes antiapoptosis attributable biology car chemokines circulating consequence cytokines exerts ikb ikkbeta impaired insulinotropic jnk jun knockout l1 obese obesity overexpressed pka rising secretion stimulated uptake