B4GALT1 and OR10G4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		B4GALT1	OR10G4
Description		beta-1,4-galactosyltransferase 1	olfactory receptor family 10 subfamily G member 4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Desmosome Filopodium Secretory Granule Membrane Brush Border Membrane Golgi Cisterna Membrane Protein-containing Complex Azurophil Granule Membrane Cell Projection Extracellular Exosome	Plasma Membrane Membrane
	Molecular Function	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity N-acetyllactosamine Synthase Activity Lactose Synthase Activity Galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Manganese Ion Binding UDP-galactosyltransferase Activity Identical Protein Binding Alpha-tubulin Binding Metal Ion Binding Beta-tubulin Binding	G Protein-coupled Receptor Activity Olfactory Receptor Activity Protein Binding
	Biological Process	Epithelial Cell Development Acute Inflammatory Response Carbohydrate Metabolic Process Lactose Biosynthetic Process Galactose Metabolic Process Protein Glycosylation Protein N-linked Glycosylation Lipid Metabolic Process Cell Adhesion Binding Of Sperm To Zona Pellucida Penetration Of Zona Pellucida Cell Population Proliferation Glycoprotein Biosynthetic Process Oligosaccharide Biosynthetic Process Extracellular Matrix Organization Wound Healing Positive Regulation Of Apoptotic Process Development Of Secondary Sexual Characteristics Epithelial Cell Proliferation Negative Regulation Of Epithelial Cell Proliferation Regulation Of Acrosome Reaction Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Angiogenesis Involved In Wound Healing Positive Regulation Of Circulating Fibrinogen Levels Macrophage Migration	Signal Transduction G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Smell Detection Of Chemical Stimulus Involved In Sensory Perception Of Smell
Pathways		Pre-NOTCH Processing in Golgi Keratan sulfate biosynthesis Interaction With Cumulus Cells And The Zona Pellucida Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective B4GALT1 causes CDG-2d Lactose synthesis Neutrophil degranulation N-Glycan antennae elongation	Olfactory Signaling Pathway Olfactory Signaling Pathway Expression and translocation of olfactory receptors
Drugs		N-Acetylglucosamine 6-Aminohexyl-uridine-C1,5'-diphosphate 4)-N-acetyl-beta-D-glucosamine Galactose-uridine-5'-diphosphate Uridine monophosphate 2-(N-morpholino)ethanesulfonic acid
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS		Aspartate aminotransferase levels ( 33547301 33339817 29403010) Blood protein levels ( 30072576) Hematocrit ( 32888494) Hemoglobin ( 32888494) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392 32128391) Influenza A (H1N1) infection ( 26379185) Iron status biomarkers (ferritin levels) ( 33536631) Mild influenza (H1N1) infection ( 26379185) N-glycan levels ( 31163085) Red blood cell count ( 32888494) Serum uric acid levels ( 30993211) Severe influenza A (H1N1) infection ( 26379185) Urate levels ( 31578528 31985003 23263486)
Interacting Genes		9 interacting genes: CDK11A EGFR LALBA OR10G4 SNCA TFRC TUBA1A TUBA4A TUBB	2 interacting genes: B4GALT1 RPL12
Entrez ID		2683	390264
HPRD ID		00659	14889
Ensembl ID		ENSG00000086062	ENSG00000254737
Uniprot IDs		B7ZAH9 P15291 Q86XA6 W6MEN3	A0A126GWS5 Q8NGN3
PDB IDs		2AE7 2AEC 2AES 2AGD 2AH9 2FY7 2FYA 2FYB 3EE5 4EE3 4EE4 4EE5 4EEA 4EEG 4EEM 4EEO 4L41 6FWT 6FWU
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Structural Constituent Of Cytoskeleton Extracellular Region Regulation Of Cellular Component Organization Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Clathrin-coated Endocytic Vesicle Membrane Positive Regulation Of Protein Localization To Cell Periphery Response To Lipid Protein-containing Complex Virus Receptor Activity Negative Regulation Of Apoptotic Process Shc-EGFR Complex Extracellular Space Multivesicular Body, Internal Vesicle Lumen Lactose Biosynthetic Process CCR7 Chemokine Receptor Binding CCL19-activated CCR7 Signaling Pathway Positive Regulation Of Dendritic Cell Dendrite Assembly Response To Desipramine Response To Iron Ion Adult Locomotory Behavior Negative Regulation Of Norepinephrine Uptake Response To Copper Ion Response To Metal Ion Regulation Of Synapse Organization Phospholipase D Inhibitor Activity Regulation Of Norepinephrine Uptake Positive Regulation Of SNARE Complex Assembly Receptor Internalization Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Hsp70 Protein Binding Transferrin Receptor Activity Protein-containing Complex Binding Microtubule Microtubule Cytoskeleton GTP Binding Cytoplasmic Ribonucleoprotein Granule Apoptotic Process Negative Regulation Of Programmed Cell Death Nucleotide Binding Enzyme Binding Regulation Of Cell Growth Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Cell Death Programmed Cell Death Lactose Synthase Activity	N-acetyllactosamine Synthase Activity Positive Regulation Of Circulating Fibrinogen Levels Lactose Biosynthetic Process Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity UDP-galactosyltransferase Activity Lactose Synthase Activity Large Ribosomal Subunit RRNA Binding Development Of Secondary Sexual Characteristics Golgi Trans Cisterna Galactosyltransferase Activity Disaccharide Metabolic Process Galactose Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Penetration Of Zona Pellucida Regulation Of Acrosome Reaction Angiogenesis Involved In Wound Healing Macrophage Migration Oligosaccharide Biosynthetic Process Binding Of Sperm To Zona Pellucida Desmosome Sperm-egg Recognition Beta-tubulin Binding Alpha-tubulin Binding Azurophil Granule Membrane Brush Border Membrane Macromolecule Biosynthetic Process Manganese Ion Binding Oligosaccharide Metabolic Process Cell-cell Recognition Cytosolic Large Ribosomal Subunit Acute Inflammatory Response Golgi Cisterna Membrane Wound Healing Protein N-linked Glycosylation Filopodium Secretory Granule Membrane Cytosolic Ribosome Mononuclear Cell Migration Carbohydrate Biosynthetic Process Cell Recognition Extracellular Exosome Cytoplasmic Translation Epithelial Cell Development Myeloid Leukocyte Migration Protein Glycosylation Macromolecule Glycosylation Negative Regulation Of Epithelial Cell Proliferation Structural Constituent Of Ribosome Glycosylation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?