OPN1MW and ARR3

Number of citations of the paper that reports this interaction (PMID 12853434)
38

Data Source:
HPRD (in vitro)

		OPN1MW	ARR3
Gene Name		opsin 1 (cone pigments), medium-wave-sensitive	arrestin 3, retinal (X-arrestin)
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Synapse
	Molecular Function	G-protein Coupled Receptor Activity Photoreceptor Activity	Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	Retinoid Metabolic Process G-protein Coupled Receptor Signaling Pathway Visual Perception Phototransduction, Visible Light Protein-chromophore Linkage Positive Regulation Of Cytokinesis	Regulation Of Protein Phosphorylation Endocytosis Signal Transduction Visual Perception
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Class A/1 (Rhodopsin-like receptors) Opsins Metabolic disorders of biological oxidation enzymes Diseases associated with visual transduction GPCR ligand binding The retinoid cycle in cones (daylight vision) GPCR downstream signaling Visual phototransduction G alpha (i) signalling events Retinoid cycle disease events
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ARR3 RANBP2	23 interactors: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 CSNK2A2 CYTH1 DVL2 FSHR GNMT MAP2K7 OPN1MW OPN4 PARK2 PLK4 PTAFR PTGDS RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		2652	407
HPRD ID		02365	02358
Ensembl ID			ENSG00000120500
Uniprot IDs		P04001	P36575
PDB IDs		1KPW	1XEH 2A34
Enriched GO Terms of Interacting Partners?		Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Negative Regulation Of Glucokinase Activity Protein Sumoylation Mitotic Nuclear Envelope Disassembly Regulation Of Phosphorylation Nuclear Envelope Disassembly Regulation Of Gluconeogenesis Regulation Of Phosphorus Metabolic Process Nuclear Envelope Organization Glucose Transport Cellular Glucose Homeostasis Hexose Transport Protein Peptidyl-prolyl Isomerization Viral Transcription Regulation Of Glucose Transport Regulation Of Glucose Metabolic Process MRNA Transport Protein Import Into Nucleus Nucleus Organization Nuclear Import Carbohydrate Transport RNA Transport RNA Localization Regulation Of Carbohydrate Metabolic Process Protein Import	Protein-chromophore Linkage Regulation Of Carbohydrate Metabolic Process Response To External Stimulus Regulation Of Cellular Process Cell Surface Receptor Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Phototransduction Detection Of Light Stimulus Regulation Of Glucose Metabolic Process Regulation Of MAPK Cascade Response To Light Stimulus Positive Regulation Of Organelle Assembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Rhodopsin Mediated Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Response To Abiotic Stimulus Cellular Metabolic Process Regulation Of JNK Cascade Bone Resorption G-protein Coupled Receptor Signaling Pathway Visual Perception Detection Of Abiotic Stimulus Sensory Perception Of Light Stimulus Signaling Mitotic Spindle Checkpoint Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Chromosome Segregation Regulation Of Kinase Activity Cell Communication Positive Regulation Of MAPK Cascade Response To Radiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Proteasomal Protein Catabolic Process Lysosomal Transport Positive Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Red, Far-red Light Phototransduction Regulation Of Cell Cycle Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Cellular Process
Tagcloud ?			arr2 arrestins arrs distributed gpcr gpcrs grk grk2 grk5 grk6 grks innate macrophages mechanistically modify responsiveness surprisingly talk tlr2 tlr3 tlr4 tlrs toll transcriptionally translational ubiquitously uncover vital
Tagcloud (Difference) ?			arr2 arrestins arrs distributed gpcr gpcrs grk grk2 grk5 grk6 grks innate macrophages mechanistically modify responsiveness surprisingly talk tlr2 tlr3 tlr4 tlrs toll transcriptionally translational ubiquitously uncover vital
Tagcloud (Intersection) ?