OPN1MW and ARR3

Number of citations of the paper that reports this interaction (PubMedID 12853434)
56

Data Source:
HPRD (in vitro)

		OPN1MW	ARR3
Description		opsin 1, medium wave sensitive	arrestin 3
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Plasma Membrane Membrane Photoreceptor Disc Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Cell Projection Synapse
	Molecular Function	G Protein-coupled Receptor Activity G Protein-coupled Photoreceptor Activity Photoreceptor Activity Identical Protein Binding	G Protein-coupled Receptor Binding Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Detection Of Visible Light Absorption Of Visible Light Positive Regulation Of Cytokinesis Cellular Response To Light Stimulus	G Protein-coupled Receptor Internalization Endocytosis Signal Transduction Visual Perception
Pathways		The retinoid cycle in cones (daylight vision) G alpha (i) signalling events Opsins Defective visual phototransduction due to OPN1MW loss of function
Drugs
Diseases		Blue cone monochromacy Colorblindness, including: Dichromacy; Anomalous trichromacy
GWAS
Interacting Genes		2 interacting genes: ARR3 RANBP2	20 interacting genes: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 DVL2 FSHR GNMT MAP2K7 MARCHF8 OPN1MW OPN4 PLK4 PTAFR RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		2652	407
HPRD ID		02365	02358
Ensembl ID		ENSG00000268221	ENSG00000120500
Uniprot IDs		P04001	P36575
PDB IDs		8Y01
Enriched GO Terms of Interacting Partners?		Opsin Binding Annulate Lamellae Cytoplasmic Periphery Of The Nuclear Pore Complex Negative Regulation Of RNA Export From Nucleus SUMO Ligase Complex Nuclear Pore Cytoplasmic Filaments G Protein-coupled Receptor Internalization Nuclear Pore Nuclear Basket Nuclear Inclusion Body Kinase Activator Activity SUMO Ligase Activity Regulation Of RNA Export From Nucleus SUMO Transferase Activity NLS-bearing Protein Import Into Nucleus Response To Amphetamine Centrosome Localization Peptidyl-prolyl Cis-trans Isomerase Activity Phosphoprotein Binding Response To Amine Toll-like Receptor Signaling Pathway Regulation Of Gluconeogenesis Protein Sumoylation Photoreceptor Inner Segment Negative Regulation Of Intracellular Transport Photoreceptor Outer Segment Receptor Internalization G Protein-coupled Receptor Binding Nuclear Pore	Photoreceptor Activity G Protein-coupled Photoreceptor Activity Thermotaxis Photoreceptor Disc Membrane G Protein-coupled Receptor Activity Detection Of Visible Light Sperm Head Plasma Membrane Absorption Of Visible Light Phototransduction Detection Of Temperature Stimulus Involved In Thermoception 11-cis Retinal Binding G Protein-coupled Receptor Signaling Pathway Response To Temperature Stimulus Detection Of Light Stimulus Positive Regulation Of MAPK Cascade Lysosome Transcytosis Regulation Of Organelle Organization Cellular Response To Light Stimulus Detection Of Temperature Stimulus Involved In Sensory Perception Uterus Development Clathrin-coated Endocytic Vesicle Detection Of Temperature Stimulus Bone Resorption Detection Of Abiotic Stimulus Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Light Stimulus Enzyme Binding Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Vacuolar Transport Regulation Of Systemic Arterial Blood Pressure Regulation Of MAPK Cascade Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Bone Remodeling Regulation Of Bone Resorption Follicle-stimulating Hormone Receptor Activity Regulation Of Acetylcholine Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Radiation Rod Bipolar Cell Differentiation RNA Polymerase III General Transcription Initiation Factor Binding Glycine N-methyltransferase Activity Positive Regulation Of ERK1 And ERK2 Cascade Visual Perception Sensory Perception Of Light Stimulus Regulation Of Macroautophagy Response To Radiation Protein Targeting To Vacuole Vasodilation Fc Receptor Signaling Pathway
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