GBP1 and FNTB

Number of citations of the paper that reports this interaction (PMID 10676968)
55

Data Source:
HPRD (in vitro)

		GBP1	FNTB
Gene Name		guanylate binding protein 1, interferon-inducible	farnesyltransferase, CAAX box, beta
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Extracellular Region Cytosol	Cytosol Microtubule Associated Complex Protein Farnesyltransferase Complex
	Molecular Function	GTPase Activity GTP Binding Identical Protein Binding	Farnesyltranstransferase Activity Protein Farnesyltransferase Activity Protein Binding Drug Binding Zinc Ion Binding Isoprenoid Binding Peptide Binding
	Biological Process	Metabolic Process Cytokine-mediated Signaling Pathway Defense Response To Virus Interferon-gamma-mediated Signaling Pathway	Phototransduction, Visible Light Negative Regulation Of Cell Proliferation Response To Inorganic Substance Response To Organic Cyclic Compound Rhodopsin Mediated Signaling Pathway Protein Farnesylation Regulation Of Rhodopsin Mediated Signaling Pathway Response To Cytokine Wound Healing Positive Regulation Of Cell Cycle Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system	Inactivation, recovery and regulation of the phototransduction cascade Visual phototransduction The phototransduction cascade Diseases associated with visual transduction
Drugs
Diseases
GWAS			Blood trace element (Zn levels) ( 23720494) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517)
Protein-Protein Interactions		2 interactors: FNTA FNTB	9 interactors: CENPF FNTA GBP1 HDAC6 HRAS KRAS PTP4A3 RAP2A RRAS2
Entrez ID		2633	2342
HPRD ID		02681	00608
Ensembl ID		ENSG00000117228	ENSG00000257365
Uniprot IDs		P32455	P49356
PDB IDs		1DG3 1F5N 2B8W 2B92 2BC9 2D4H	1JCQ 1LD7 1LD8 1MZC 1S63 1SA4 1TN6 2F0Y 2H6F 2H6G 2H6H 2H6I 2IEJ 3E37
Enriched GO Terms of Interacting Partners?		Protein Farnesylation Protein Prenylation Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Detection Of Light Stimulus Cellular Response To Radiation Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Positive Regulation Of Tubulin Deacetylation Response To Light Stimulus Response To Radiation Regulation Of Tubulin Deacetylation Positive Regulation Of Deacetylase Activity Detection Of Stimulus Protein Geranylgeranylation Neurotransmitter Receptor Metabolic Process Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Positive Regulation Of Protein Deacetylation Response To Abiotic Stimulus G-protein Coupled Receptor Signaling Pathway Regulation Of Protein Deacetylation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Fibroblast Proliferation Response To External Stimulus Execution Phase Of Apoptosis Receptor Metabolic Process Regulation Of Fibroblast Proliferation Regulation Of Receptor Activity Response To Organic Substance Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Signal Transduction Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Signaling Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle	Ras Protein Signal Transduction Positive Regulation Of Rac Protein Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cell Migration Response To Growth Factor Small GTPase Mediated Signal Transduction Regulation Of Cell Motility Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Locomotion Regulation Of Synaptic Transmission, GABAergic Regulation Of Cellular Component Movement Regulation Of Rac Protein Signal Transduction Social Behavior Epithelial Tube Branching Involved In Lung Morphogenesis Regulation Of Neuron Death Positive Regulation Of Ras Protein Signal Transduction Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Response To Light Stimulus Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Small GTPase Mediated Signal Transduction Visual Learning Response To External Stimulus Positive Regulation Of Locomotion Visual Behavior Activation Of MAPKK Activity Lung Morphogenesis Cellular Response To Organic Substance Regulation Of Oxidoreductase Activity Positive Regulation Of Tubulin Deacetylation Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Hsp90 Deacetylation Associative Learning Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Response To Radiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Muscle Structure Development Positive Regulation Of Chaperone-mediated Protein Complex Assembly Polyubiquitinated Misfolded Protein Transport Regulation Of Receptor Activity Cell Communication Cellular Response To Growth Factor Stimulus Response To Organic Substance Learning Actin Cytoskeleton Organization
Tagcloud ?		advance cdc25a cohorts dach1 demonstrating doi dpyd endocrine exerting former functionally fyn itpr1 june lyn mcf onc oncogene online overcome parental prkca prlr publication restored s0 subcellular tamoxifen tamr	annotation atad5 automatically becn1 cdkn2a centered clusterone cytoscape david e2f e2f1 geneways kegg kras language module modules mp neurofibromatosis nf1 nf2 nsclc orthologous phenotypes proven successively systemically thyroglobulin visualization
Tagcloud (Difference) ?		advance cdc25a cohorts dach1 demonstrating doi dpyd endocrine exerting former functionally fyn itpr1 june lyn mcf onc oncogene online overcome parental prkca prlr publication restored s0 subcellular tamoxifen tamr	annotation atad5 automatically becn1 cdkn2a centered clusterone cytoscape david e2f e2f1 geneways kegg kras language module modules mp neurofibromatosis nf1 nf2 nsclc orthologous phenotypes proven successively systemically thyroglobulin visualization
Tagcloud (Intersection) ?