EHF and FRZB

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		EHF	FRZB
Gene Name		ets homologous factor	frizzled-related protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus	Extracellular Space Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	G-protein Coupled Receptor Activity Wnt-protein Binding Wnt-activated Receptor Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Cell Proliferation Epithelial Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Skeletal System Development Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Negative Regulation Of Cartilage Development Somite Development Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Obesity-related traits ( 23251661) Response to antipsychotic treatment ( 21107309) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Volumetric brain MRI ( 17903297)	Waist-to-hip circumference ratio (interaction) ( 23192594)
Protein-Protein Interactions		1 interactors: FRZB	7 interactors: BBS10 EHF ELF5 PNO1 POLA2 RBX1 SMAD1
Entrez ID		26298	2487
HPRD ID		16105	07282
Ensembl ID			ENSG00000162998
Uniprot IDs		Q9NZC4	D9ZGF6 Q92765
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Hepatocyte Differentiation Convergent Extension Involved In Organogenesis Convergent Extension Cochlea Morphogenesis Non-canonical Wnt Signaling Pathway Negative Regulation Of Cartilage Development Negative Regulation Of Epithelial Cell Differentiation Cochlea Development Positive Regulation Of Fat Cell Differentiation Neural Crest Cell Differentiation Regulation Of Cartilage Development Somite Development Inner Ear Morphogenesis Ear Morphogenesis Regulation Of Fat Cell Differentiation Mesenchymal Cell Differentiation Regulation Of Epithelial Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cell Growth Inner Ear Development Negative Regulation Of Wnt Signaling Pathway Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Ear Development Negative Regulation Of Growth Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Stem Cell Differentiation Embryonic Organ Morphogenesis Negative Regulation Of Cell Development Regulation Of Cell Growth	Regulation Of Transcription From RNA Polymerase II Promoter Cell Proliferation Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Primary MiRNA Processing Positive Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Epithelium Development Cellular Aromatic Compound Metabolic Process Osteoblast Fate Commitment Cellular Nitrogen Compound Metabolic Process Protein Neddylation SMAD Protein Complex Assembly Cellular Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Homeostatic Process Chaperone-mediated Protein Complex Assembly Mesodermal Cell Fate Commitment Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cardiac Muscle Cell Proliferation Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Cellular Biosynthetic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Mammary Gland Epithelial Cell Differentiation Nuclear DNA Replication Telomere Maintenance Via Recombination Cellular Macromolecule Biosynthetic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Ectoderm Development Tissue Development Nonmotile Primary Cilium Assembly Mesodermal Cell Differentiation Macromolecule Biosynthetic Process Epithelial Cell Differentiation Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Cell Fate Commitment Involved In Formation Of Primary Germ Layer Protein Import Into Nucleus, Translocation DNA Strand Elongation Cardiac Muscle Tissue Growth Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Photoreceptor Cell Maintenance DNA Replication Initiation
Tagcloud ?		acquired barrier came clear congo contact democratic died ebola epidemic females fever fluids general hemorrhagic hospital hospitalized hygienic kikwit males mosango never outbreak probably recognized relatively republic soon twenty	abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt7a wnt9a
Tagcloud (Difference) ?		acquired barrier came clear congo contact democratic died ebola epidemic females fever fluids general hemorrhagic hospital hospitalized hygienic kikwit males mosango never outbreak probably recognized relatively republic soon twenty	abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt7a wnt9a
Tagcloud (Intersection) ?