FBXO3 and CFAP410

Number of citations of the paper that reports this interaction (PubMedID 32891887)
53

Data Source:
BioGRID (pull down)

		FBXO3	CFAP410
Description		F-box protein 3	cilia and flagella associated protein 410
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Photoreceptor Outer Segment Nucleoplasm Cytoplasm Mitochondrion Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Photoreceptor Cell Cilium
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding
	Biological Process	Transcription By RNA Polymerase II Proteolysis Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Lipopolysaccharide	DNA Damage Response Cytoskeleton Organization Smoothened Signaling Pathway Regulation Of Cell Shape Cell Projection Organization Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Coronary artery calcification ( 23870195) Fruit consumption ( 32066663) Morning person ( 30696823)
Interacting Genes		4 interacting genes: CFAP410 SKP1 SMURF1 UBC	4 interacting genes: ATOX1 FBXO3 GMCL1 SPG21
Entrez ID		26273	755
HPRD ID		16433	04427
Ensembl ID		ENSG00000110429	ENSG00000160226
Uniprot IDs		Q49AF1 Q9UK99	O43822
PDB IDs		5HDW 9KBD 9KBF	8AXR
Enriched GO Terms of Interacting Partners?		Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Modification-dependent Protein Catabolic Process Protein Modification By Small Protein Conjugation Engulfment Of Target By Autophagosome F-box Domain Binding Post-translational Protein Modification Cul7-RING Ubiquitin Ligase Complex Photoreceptor Cell Cilium Regulation Of Cell Morphogenesis Positive Regulation Of Anoikis Macromolecule Catabolic Process Protein Polyubiquitination Ubiquitin Ligase Complex Scaffold Activity Activin Receptor Binding Substrate Localization To Autophagosome Proteolysis Ubiquitin Ligase Activator Activity
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