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FBXO3

Description F-box protein 3
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • SCF Ubiquitin Ligase Complex
Molecular Function
  • Ubiquitin-protein Transferase Activity
  • Protein Binding
  • Ubiquitin-like Ligase-substrate Adaptor Activity
Biological Process
  • Transcription By RNA Polymerase II
  • Proteolysis
  • Protein Ubiquitination
  • SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS
  • Chronotype ( 30696823)
  • Coronary artery calcification ( 23870195)
  • Fruit consumption ( 32066663)
  • Morning person ( 30696823)
Novel Interacting Genes 1 novel interacting genes: CRYBA1
Interacting Genes 4 interacting genes: CFAP410 SKP1 SMURF1 UBC
Entrez ID 26273
HPRD ID 16433
Ensembl ID ENSG00000110429
Uniprot IDs Q49AF1 Q9UK99
PDB IDs 5HDW 9KBD 9KBF
Enriched GO Terms of Interacting Partners?
  • Proteolysis Involved In Protein Catabolic Process
  • Protein Ubiquitination
  • Modification-dependent Protein Catabolic Process
  • Protein Modification By Small Protein Conjugation
  • Engulfment Of Target By Autophagosome
  • F-box Domain Binding
  • Post-translational Protein Modification
  • Cul7-RING Ubiquitin Ligase Complex
  • Photoreceptor Cell Cilium
  • Regulation Of Cell Morphogenesis
  • Positive Regulation Of Anoikis
  • Macromolecule Catabolic Process
  • Protein Polyubiquitination
  • Ubiquitin Ligase Complex Scaffold Activity
  • Activin Receptor Binding
  • Substrate Localization To Autophagosome
  • Proteolysis
  • Ubiquitin Ligase Activator Activity
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