DRC4 and GSTA4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DRC4	GSTA4
Description		dynein regulatory complex subunit 4	glutathione S-transferase alpha 4
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Axoneme Microtubule Cytoskeleton Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection 9+2 Motile Cilium	Cytoplasm Cytosol
	Molecular Function	Protein Binding Microtubule Binding Small GTPase Binding	Glutathione Transferase Activity Protein Binding Transferase Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Microtubule Cytoskeleton Organization Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Brain Development Intracellular Protein Localization Negative Regulation Of Cell Population Proliferation Flagellated Sperm Motility Axoneme Assembly Positive Regulation Of Smoothened Signaling Pathway Cell Motility Establishment Of Localization In Cell Cilium Movement Involved In Cell Motility Positive Regulation Of Protein Localization To Cilium	Glutathione Metabolic Process Xenobiotic Metabolic Process
Pathways		Activation of SMO	Glutathione conjugation
Drugs			Glutathione
Diseases
GWAS			Arterial stiffness index ( 31235810) Epilepsy (remission after treatment) ( 23962720) Nose size ( 27182965) Staphylococcus aureus nasal carriage (intermittent) ( 26569114)
Interacting Genes		110 interacting genes: ARL6IP1 BCAR3 BORCS6 BYSL C1orf35 CARD10 CARD9 CBFA2T3 CCDC125 CCDC146 CCDC6 CCHCR1 CCNG1 CDC37 CDR2 CEP70 CFAP53 CINP CKS1B COG6 CPSF7 CRYBB1 CT45A1 CWF19L2 CYSRT1 DAXX DDX17 DISC1 DMAP1 EAF1 EHHADH EIF1AD ERCC1 EVI5L FAM161A FAM161B FHL2 GADD45GIP1 GCC1 GEM GOLGA2 GPRASP3 GRIPAP1 GSTA4 HEXIM2 HOMER3 HOMEZ HOXA1 HSF2BP IGFBP6 KDM1A KRT14 KRT15 KRT16 L3MBTL2 L3MBTL3 LASP1 LHX3 LMO1 LMO2 LZTS1 MAD1L1 MFAP1 MID2 MRFAP1L1 NDOR1 NKAPD1 PLK4 PNKP PNMA5 POLR1C POTEB3 PPFIA1 PRDM14 PRMT5 PRPF18 RALBP1 RBAK RINT1 RUBCN SCNM1 SKIL SORBS3 SP7 SPATA18 SPG21 STAC3 TCEA2 THAP1 TNFAIP3 TRAF2 TRAF5 TRIM41 TRIM54 TSFM TSGA10IP TXLNA TXLNB USHBP1 YES1 YJU2 ZBTB22 ZBTB26 ZBTB39 ZNF212 ZNF250 ZNF572 ZNF620 ZNF629 ZNF792	5 interacting genes: CIMIP5 DRC4 GSTA2 LSM1 NTAQ1
Entrez ID		2622	2941
HPRD ID		05533	06899
Ensembl ID		ENSG00000141013	ENSG00000170899
Uniprot IDs		A0A087WZT7 A0A384MR00 B7Z1U9 O95995	O15217
PDB IDs		8J07	1GUL 1GUM 3IK7
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling	Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity
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