GSTA4

Gene Name		glutathione S-transferase alpha 4
Image
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Glutathione Transferase Activity Protein Homodimerization Activity
	Biological Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Small Molecule Metabolic Process Glutathione Derivative Biosynthetic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs		Glutathione
Diseases
GWAS
Protein-protein Interactions		2 interactors: C2orf50 GSTA2
Entrez ID		2941
HPRD ID		06899
Ensembl ID		ENSG00000170899
Uniprot IDs		O15217 Q6P4G1
PDB IDs		1GUL 1GUM 3IK7
Enriched GO Terms of Interacting Partners?		Glutathione Derivative Biosynthetic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Peptide Metabolic Process Cellular Modified Amino Acid Metabolic Process Cellular Amide Metabolic Process Sulfur Compound Metabolic Process
Tagcloud ?