TTLL3 and CDCA5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TTLL3	CDCA5
Gene Name		tubulin tyrosine ligase-like family member 3	cell division cycle associated 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Cilium Axoneme Microtubule Cytoskeleton	Chromosome, Centromeric Region Nuclear Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane Cohesin Complex
	Molecular Function	Protein-glycine Ligase Activity Protein-glycine Ligase Activity, Initiating	Chromatin Binding Protein Binding
	Biological Process	Protein Polyglycylation Axoneme Assembly Cilium Assembly	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Double-strand Break Repair Mitotic Sister Chromatid Cohesion Mitotic Nuclear Division Mitotic Chromosome Condensation Mitotic Metaphase Plate Congression Cell Division Regulation Of Cohesin Localization To Chromatin
Pathways			Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase S Phase Mitotic Metaphase and Anaphase M Phase Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: CDCA5	7 interactors: CDK1 IRAK3 KDM1A RPAIN SENP2 TTLL3 XRCC6
Entrez ID		26140	113130
HPRD ID		15585	13016
Ensembl ID		ENSG00000214021	ENSG00000146670
Uniprot IDs		J3KQB2 Q9Y4R7	Q96FF9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cohesin Localization To Chromatin Mitotic Sister Chromatid Cohesion Regulation Of Sister Chromatid Cohesion Mitotic Metaphase Plate Congression Mitotic Chromosome Condensation Sister Chromatid Cohesion Metaphase Plate Congression Establishment Of Chromosome Localization Chromosome Condensation Mitotic Sister Chromatid Segregation Regulation Of Chromosome Segregation Sister Chromatid Segregation Double-strand Break Repair G1/S Transition Of Mitotic Cell Cycle DNA Packaging Regulation Of Chromosome Organization Chromosome Segregation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Conformation Change Mitotic Nuclear Division Establishment Of Organelle Localization Organelle Localization Cell Division Regulation Of Cell Cycle Process	Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Protein Binding Negative Regulation Of Intracellular Signal Transduction MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Macrophage Tolerance Induction Regulation Of Primitive Erythrocyte Differentiation Pronuclear Fusion Negative Regulation Of Binding Toll-like Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Embryonic Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Repair Positive Regulation Of Gene Expression Protein Polyglycylation Regulation Of DNA Replication Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Cellular Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Protein Modification Process Activation Of Innate Immune Response Regulation Of Protein Binding Cellular Hyperosmotic Salinity Response Regulation Of Intracellular Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Muscle Cell Development Negative Regulation Of Macrophage Cytokine Production Positive Regulation Of Innate Immune Response Regulation Of Cellular Protein Metabolic Process Protein Desumoylation Cellular Response To DNA Damage Stimulus Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To X-ray Positive Regulation Of Immune System Process Immune System Process Negative Regulation Of Chromatin Binding Regulation Of Schwann Cell Differentiation DNA Recombination Regulation Of Protein Metabolic Process Histone H3-K9 Demethylation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K4 Demethylation Establishment Of Integrated Proviral Latency Regulation Of Innate Immune Response Regulation Of Binding Chromosome Organization
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