KLK13 and B4GALT2

		KLK13	B4GALT2
Description		kallikrein related peptidase 13	beta-1,4-galactosyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Secretory Granule	Golgi Membrane Nucleoplasm Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity N-acetyllactosamine Synthase Activity Lactose Synthase Activity Protein Binding Galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Metal Ion Binding
	Biological Process	Proteolysis Protein Processing Protein Maturation	Carbohydrate Metabolic Process Protein Glycosylation Brain Development Memory Locomotory Behavior Visual Learning Cerebellar Purkinje Cell Layer Development Glycosylation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Formation of the cornified envelope	Keratan sulfate biosynthesis N-Glycan antennae elongation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576)
Interacting Genes		3 interacting genes: A2M SERPINA3 SERPINF2	3 interacting genes: GPR35 MEOX2 PFDN6
Entrez ID		26085	8704
HPRD ID		05693	04928
Ensembl ID		ENSG00000167759	ENSG00000117411
Uniprot IDs		M0R218 Q5BQ99 Q86VI7 Q9UKR3	O60909
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Alpha Granule Lumen Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity Blood Microparticle Acute-phase Response Endopeptidase Inhibitor Activity Extracellular Matrix Acute Inflammatory Response Protease Binding Negative Regulation Of Complement Activation, Lectin Pathway Interleukin-8 Binding Lactose Synthase Activity N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Tumor Necrosis Factor Binding Interleukin-1 Binding Negative Regulation Of Plasminogen Activation Galactosyltransferase Activity Fibrinogen Complex Extracellular Space System Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Cerebellar Purkinje Cell Layer Development Negative Regulation Of Fibrinolysis Negative Regulation Of Complement Activation Regulation Of Fibrinolysis Regulation Of Plasminogen Activation Regulation Of Complement Activation Maintenance Of Gastrointestinal Epithelium Inflammatory Response Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Blood Coagulation Fibrinolysis Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Positive Regulation Of Collagen Biosynthetic Process Extracellular Exosome Extracellular Region Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Positive Regulation Of Coagulation Epithelial Structure Maintenance Regulation Of Collagen Biosynthetic Process Regulation Of Collagen Metabolic Process Regulation Of Systemic Arterial Blood Pressure Growth Factor Binding Regulation Of Humoral Immune Response Negative Regulation Of Blood Coagulation	Contractile Muscle Fiber
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