KLK13

Description		kallikrein related peptidase 13
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Secretory Granule
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Protein Processing Protein Maturation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Novel Interacting Genes		1 novel interacting genes: B4GALT2
Interacting Genes		3 interacting genes: A2M SERPINA3 SERPINF2
Entrez ID		26085
HPRD ID		05693
Ensembl ID		ENSG00000167759
Uniprot IDs		M0R218 Q5BQ99 Q86VI7 Q9UKR3
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Alpha Granule Lumen Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity Blood Microparticle Acute-phase Response Endopeptidase Inhibitor Activity Extracellular Matrix Acute Inflammatory Response Protease Binding Negative Regulation Of Complement Activation, Lectin Pathway Interleukin-8 Binding Lactose Synthase Activity N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Tumor Necrosis Factor Binding Interleukin-1 Binding Negative Regulation Of Plasminogen Activation Galactosyltransferase Activity Fibrinogen Complex Extracellular Space System Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Cerebellar Purkinje Cell Layer Development Negative Regulation Of Fibrinolysis Negative Regulation Of Complement Activation Regulation Of Fibrinolysis Regulation Of Plasminogen Activation Regulation Of Complement Activation Maintenance Of Gastrointestinal Epithelium Inflammatory Response Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Blood Coagulation Fibrinolysis Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Positive Regulation Of Collagen Biosynthetic Process Extracellular Exosome Extracellular Region Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Positive Regulation Of Coagulation Epithelial Structure Maintenance Regulation Of Collagen Biosynthetic Process Regulation Of Collagen Metabolic Process Regulation Of Systemic Arterial Blood Pressure Growth Factor Binding Regulation Of Humoral Immune Response Negative Regulation Of Blood Coagulation
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