PTCD1 and SYP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PTCD1	SYP
Description		pentatricopeptide repeat domain 1	synaptophysin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuromuscular Junction Presynaptic Membrane Neuron Projection Terminal Bouton Neuron Projection Terminus Synapse Perinuclear Region Of Cytoplasm Presynaptic Active Zone Excitatory Synapse Schaffer Collateral - CA1 Synapse Presynapse
	Molecular Function	TRNA Binding RNA Binding Protein Binding	Protein Binding Cholesterol Binding SH2 Domain Binding Identical Protein Binding
	Biological Process	TRNA Processing Mitochondrial Translation TRNA 3'-end Processing	Endocytosis Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Maturation Regulation Of Neuronal Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Modulation Of Chemical Synaptic Transmission Regulation Of Opioid Receptor Signaling Pathway
Pathways			Sensory processing of sound by inner hair cells of the cochlea
Drugs
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS		Adult body size ( 32376654) Facial emotion recognition (sad faces) ( 28608620) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Tacrolimus trough concentration in kidney transplant patients ( 29160300)
Interacting Genes		8 interacting genes: CARD10 CFTR FKBP7 GEMIN4 MTUS2 NFKBID SYP TFIP11	41 interacting genes: AP1G1 ARFIP2 CAND2 CD160 DIABLO FARS2 GAB1 GDNF GRB2 HSFX1 HSFX2 JOSD2 LNPK MIEF1 MIEF2 MRM1 MRRF MTERF3 MYG1 NDRG4 PBX3 PITPNC1 PLIN3 PNKP PPIF PTCD1 PTPN9 RBFA SH3GLB1 SIAH1 SIAH2 SMG9 SNX1 SPG21 SSX5 STARD4 THAP4 TUFM VAMP2 WDFY2 WIPI2
Entrez ID		26024	6855
HPRD ID		11463	02435
Ensembl ID		ENSG00000106246	ENSG00000102003
Uniprot IDs		A4D273 O75127	P08247
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Natural Killer Cell Degranulation Dorsal Spinal Cord Development Mitochondrion Mitochondrial Matrix Mitochondrial Outer Membrane
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