TPGS2 and OTP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TPGS2	OTP
Description		tubulin polyglutamylase complex subunit 2	orthopedia homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Centriolar Satellite	Chromatin Fibrillar Center Nucleus Nucleoplasm Nuclear Body
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Polymerization Cilium Disassembly	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuroblast Proliferation Regulation Of DNA-templated Transcription Nervous System Development Neuroblast Proliferation Forebrain Neuron Differentiation Hypothalamus Cell Differentiation Neurohypophysis Development Cell Differentiation Neuron Differentiation Neuroendocrine Cell Differentiation Dopaminergic Neuron Differentiation
Pathways		Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Periodontal disease-related phenotype (Socransky) ( 24347629)	Age at first sexual intercourse ( 34211149)
Interacting Genes		3 interacting genes: EWSR1 OTP ZDHHC17	8 interacting genes: BEX1 CCL21 CDK6 CPNE7 EOMES PDE6D SLC12A7 TPGS2
Entrez ID		25941	23440
HPRD ID		12684	05166
Ensembl ID		ENSG00000134779	ENSG00000171540
Uniprot IDs		A0A087WUC8 A0A087X1R7 K7EKC0 Q68CL5	Q5XKR4
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Neurohypophysis Development Protein-cysteine S-myristoyltransferase Activity Hypothalamus Cell Differentiation Protein-cysteine S-stearoyltransferase Activity Lipoprotein Transport Regulation Of Neurotrophin TRK Receptor Signaling Pathway Protein Palmitoylation Palmitoyltransferase Activity Regulation Of Modification Of Synaptic Structure Golgi-associated Vesicle Membrane Protein-cysteine S-palmitoyltransferase Activity Neuroendocrine Cell Differentiation Protein Lipidation Positive Regulation Of Neuroblast Proliferation	Positive Regulation Of Cell-matrix Adhesion Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex FBXO Family Protein Binding Dendritic Cell Dendrite Assembly Positive Regulation Of Myeloid Dendritic Cell Chemotaxis Mesangial Cell-matrix Adhesion CCR7 Chemokine Receptor Binding CCL21-activated CCR7 Signaling Pathway Negative Regulation Of Dendritic Cell Dendrite Assembly CD8-positive, Alpha-beta T Cell Differentiation Involved In Immune Response Regulation Of Cell-matrix Adhesion Stem Cell Differentiation Neurogenesis Positive Regulation Of Cell-substrate Adhesion Regulation Of Dendritic Cell Dendrite Assembly Mesodermal To Mesenchymal Transition Involved In Gastrulation
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