OTP and CPNE7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OTP	CPNE7
Description		orthopedia homeobox	copine 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm Nuclear Body	Nucleus Cytoplasm Plasma Membrane Membrane Synapse Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuroblast Proliferation Regulation Of DNA-templated Transcription Nervous System Development Neuroblast Proliferation Forebrain Neuron Differentiation Hypothalamus Cell Differentiation Neurohypophysis Development Cell Differentiation Neuron Differentiation Neuroendocrine Cell Differentiation Dopaminergic Neuron Differentiation	Lipid Metabolic Process Cellular Response To Calcium Ion
Pathways			Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149)	Age at first sexual intercourse ( 27089180) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Smoking behaviour (cigarette pack-years) ( 30679032)
Interacting Genes		8 interacting genes: BEX1 CCL21 CDK6 CPNE7 EOMES PDE6D SLC12A7 TPGS2	28 interacting genes: ADAMTSL4 CALCOCO2 CSNK2B DDIT4L DUSP21 EFHC2 GPX7 KRT75 LHX3 MEOX2 NECAB1 OTP PBX4 PICK1 PKLR REL SAXO1 TEPSIN TRIM23 TRIM27 ZFP90 ZMIZ2 ZNF18 ZNF474 ZNF572 ZNF655 ZNF774 ZRANB1
Entrez ID		23440	27132
HPRD ID		05166	05749
Ensembl ID		ENSG00000171540	ENSG00000178773
Uniprot IDs		Q5XKR4	Q9UBL6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell-matrix Adhesion Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex FBXO Family Protein Binding Dendritic Cell Dendrite Assembly Positive Regulation Of Myeloid Dendritic Cell Chemotaxis Mesangial Cell-matrix Adhesion CCR7 Chemokine Receptor Binding CCL21-activated CCR7 Signaling Pathway Negative Regulation Of Dendritic Cell Dendrite Assembly CD8-positive, Alpha-beta T Cell Differentiation Involved In Immune Response Regulation Of Cell-matrix Adhesion Stem Cell Differentiation Neurogenesis Positive Regulation Of Cell-substrate Adhesion Regulation Of Dendritic Cell Dendrite Assembly Mesodermal To Mesenchymal Transition Involved In Gastrulation	Metal Ion Binding Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Regulation Of Transcription By RNA Polymerase II
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